Function and therapeutic value of astrocytes in neurological diseases
Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
Astrocyte crosstalk in CNS inflammation
M Linnerbauer, MA Wheeler, FJ Quintana - Neuron, 2020 - cell.com
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Identification of ligand–receptor pairs that drive human astrocyte development
Extrinsic signaling between diverse cell types is crucial for nervous system development.
Ligand binding is a key driver of developmental processes. Nevertheless, it remains a …
Ligand binding is a key driver of developmental processes. Nevertheless, it remains a …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
Protective functions of reactive astrocytes following central nervous system insult
M Linnerbauer, V Rothhammer - Frontiers in immunology, 2020 - frontiersin.org
Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …
[HTML][HTML] Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification
Precise temporal control of gene expression in neuronal progenitors is necessary for correct
regulation of neurogenesis and cell fate specification. However, the cellular heterogeneity of …
regulation of neurogenesis and cell fate specification. However, the cellular heterogeneity of …
Neuroinflammation: An astrocyte perspective
Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
[PDF][PDF] Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …
tube determines the identity of neural progenitors and the function and physiology of the …
[HTML][HTML] Establishing neuronal diversity in the spinal cord: a time and a place
The vertebrate spinal cord comprises multiple functionally distinct neuronal cell types
arranged in characteristic positions. During development, these different types of neurons …
arranged in characteristic positions. During development, these different types of neurons …
[HTML][HTML] The neuropeptide Tac2 controls a distributed brain state induced by chronic social isolation stress
Chronic social isolation causes severe psychological effects in humans, but their neural
bases remain poorly understood. 2 weeks (but not 24 hr) of social isolation stress (SIS) …
bases remain poorly understood. 2 weeks (but not 24 hr) of social isolation stress (SIS) …