[HTML][HTML] G-quadruplexes at telomeres: friend or foe?

TM Bryan - Molecules, 2020 - mdpi.com
Telomeres are DNA-protein complexes that cap and protect the ends of linear
chromosomes. In almost all species, telomeric DNA has a G/C strand bias, and the short …

Folding dynamics of polymorphic G‐quadruplex structures

JT Grün, H Schwalbe - Biopolymers, 2022 - Wiley Online Library
Abstract G‐quadruplexes (G4), found in numerous places within the human genome, are
involved in essential processes of cell regulation. Chromosomal DNA G4s are involved for …

Identification of the new type of G-quadruplex with multiple vacant sites in human telomeric DNA

X Zhang, X Kou, W Zhang, W Zhang - CCS Chemistry, 2022 - chinesechemsoc.org
To date, few studies have reported on the folding mechanism of tandem G-quadruplexes in
human telomeric DNA. Hence, the control of the biofunctions of G-quadruplex, which …

G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C–T base-pair

J Marquevielle, A De Rache, B Vialet… - Nucleic acids …, 2022 - academic.oup.com
The Caenorhabditis elegans model has greatly contributed to the understanding of the role
of G-quadruplexes in genomic instability. The GGCTTA repeats of the C. elegans telomeres …

Effects of Sequence and Base Composition on the CD and TDS Profiles of i‐DNA

N Iaccarino, M Cheng, D Qiu, B Pagano… - Angewandte Chemie …, 2021 - Wiley Online Library
The i‐motif DNA, also known as i‐DNA, is a non‐canonical DNA secondary structure formed
by cytosine‐rich sequences, consisting of two intercalated parallel‐stranded duplexes held …

A General Framework to Interpret Hydrogen–Deuterium Exchange Native Mass Spectrometry of G-Quadruplex DNA

E Largy, M Ranz, V Gabelica - Journal of the American Chemical …, 2023 - ACS Publications
G-quadruplexes (G4s) are secondary structures formed by guanine-rich oligonucleotides
involved in various biological processes. However, characterizing G4s is challenging …

[HTML][HTML] Structural motifs and intramolecular interactions in non-canonical G-quadruplexes

J Jana, S Mohr, YM Vianney, K Weisz - RSC Chemical Biology, 2021 - pubs.rsc.org
Guanine (G)-rich DNA or RNA sequences can assemble or intramolecularly fold into G-
quadruplexes formed through the stacking of planar G· G· G· G tetrads in the presence of …

Parallel G-triplexes and G-hairpins as potential transitory ensembles in the folding of parallel-stranded DNA G-Quadruplexes

P Stadlbauer, P Kührová, L Vicherek… - Nucleic acids …, 2019 - academic.oup.com
Guanine quadruplexes (G4s) are non-canonical nucleic acids structures common in
important genomic regions. Parallel-stranded G4 folds are the most abundant, but their …

[HTML][HTML] Genome-wide discovery of G-quadruplexes in barley

HB Cagirici, H Budak, TZ Sen - Scientific Reports, 2021 - nature.com
Abstract G-quadruplexes (G4s) are four-stranded nucleic acid structures with closely spaced
guanine bases forming square planar G-quartets. Aberrant formation of G4 structures has …

De Novo Mutation Rate Variation and Its Determinants in Chlamydomonas

E López-Cortegano, RJ Craig, J Chebib… - Molecular Biology …, 2021 - academic.oup.com
De novo mutations are central for evolution, since they provide the raw material for natural
selection by regenerating genetic variation. However, studying de novo mutations is …