Novel boron‐containing compound, halogenated boroxine, induces selective cytotoxicity through apoptosis triggering in UT‐7 leukemia

M Hadzic, L Pojskic, N Lojo‐Kadric… - … of Biochemical and …, 2022 - Wiley Online Library
Apoptosis induction is a promising approach in targeting tumor cells. As halogenated
boroxine (HB) shows antitumor activity, but its mechanism of action in hematological tumors …

Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium‐trioxohydroxytetrafluorotriborate K2[B3O3F4OH]

J Ostojic, S Herenda, S Galijasevic, B Galic… - Journal of …, 2017 - Wiley Online Library
Recently research shows that horseradish peroxidase, HRP, when combined with other
compounds, is highly reactive toward different human tumour cells and that better …

Genotoxic and Antimutagenic Activity of Ficus carica Extracts

N Yasmeen, G Usha kiranmai, AS Sameer - Fig (Ficus carica): Production …, 2023 - Springer
Genotoxicity assessment is indispensable in analyzing various substances such as
cosmetics, natural products, food beverages, etc. The sole intent is to raise the safety …

Effects of dipotassium-trioxohydroxytetrafluorotriborate, K2[B3O3F4OH], on cell viability and gene expression of common human cancer drug targets in a …

L Pojskic, S Haveric, N Lojo-Kadric… - Journal of enzyme …, 2016 - Taylor & Francis
Recently it was found that dipotassium-trioxohydroxytetrafluorotriborate, K2 (B3O3F4OH), is
a potent and highly specific inhibitor of precancerous cell processes. We conducted gene …

Impact of calcium ion on cytotoxic effect of the boroxine derivative, K2[B3O3F4OH]

S Ivankovic, R Stojkovic, M Maksimovic… - Journal of enzyme …, 2016 - Taylor & Francis
The effect of Ca2+ ions on the cytotoxic ability of boron heterocyclic compound dipotassium-
trioxohydroxytetrafluorotriborate (K2 [B3O3F4OH]), on in vitro tumor cells (mammary …

Biochemical and histomorphological findings in Swiss Wistar rats treated with potential boron-containing therapeutic-K2 [B3O3F4OH]

A Haverić, A Durmić-Pašić, A Alić, I Mujezinović… - Journal of Trace …, 2020 - Elsevier
Background Boron and boron containing compounds are known for their biological and
protective roles being non-toxic and non-mutagenic in low concentrations. Male rats were …

Bioflavonoids protect cells against halogenated boroxine-induced genotoxic damage by upregulation of hTERT expression

M Hadzic, S Haveric, A Haveric… - … für Naturforschung C, 2019 - degruyter.com
Plant bioflavonoids are widely present in the human diet and have various protective
properties. In this study, we have demonstrated the capacity of delphinidin and luteolin to …

Moderate Toxicity of Potential Boron-containing Therapeutic, Dipotassium-trioxohydroxytetrafl uorotriborate -K2(B3O3F4OH) in Rats and Mice

A Haveric, S Haveric, M Hadzic, J Ezic… - Brazilian Journal of …, 2023 - SciELO Brasil
Biological activity of boron-containing compounds (BCCs) has been well-known. Growing
interest and numerous applications for BCCs have been reported. Boron and boron …

Halogenated Boroxine K2[B3O3F4OH] Modulates Metabolic Phenotype and Autophagy in Human Bladder Carcinoma 5637 Cell Line

N Elez-Burnjaković, L Pojskić, A Haverić, N Lojo-Kadrić… - Molecules, 2024 - mdpi.com
Halogenated boroxine K2 [B3O3F4OH](HB), an inorganic derivative of cyclic anhydride of
boronic acid, is patented as a boron-containing compound with potential for the treatment of …

Genotoxicity Evaluation of Dipotassium -Trioxohydroxytetrafluorotriborate, K2(B3O3F4OH), in Human Lymphocyte Cultures and Mice Reticulocytes

S Haveric, M Hadzic, A Haveric, M Mijanovic… - Brazilian Archives of …, 2016 - SciELO Brasil
Genotoxic effects of inorganic molecule dipotassium-trioxohydroxytetrafluorotriborate, K2
(B3O3F4OH), a promising new therapeutic for the epidermal changes treatment, have been …