The limited efficacy of the current antitumor microenvironment strategies is due in part to the
poor understanding of the roles and relative contributions of the various tumor stromal cells …

Lung cancer remains a major global health problem because of its high cancer-related
mortality rate despite advances in therapeutic approaches. Non-small cell lung cancer …

Bacillus anthracis causes anthrax through a combination of bacterial infection and toxemia.
As a major virulence factor of B. anthracis, anthrax lethal toxin (LT) is a zinc-dependent …

Recently, there has been great interest in plant-derived compounds known as
phytochemicals. The pentacyclic oleanane-, ursane-, and lupane-type triterpenes are …

Anthrax lethal toxin (PrAg/LF) is a binary toxin consisting of protective antigen (PrAg), the
cell binding moiety, and lethal factor (LF), the catalytic moiety. Inside the cell, LF cleaves …