[HTML][HTML] Global discovery of lupus genetic risk variant allelic enhancer activity
Genome-wide association studies of Systemic Lupus Erythematosus (SLE) nominate 3073
genetic variants at 91 risk loci. To systematically screen these variants for allelic …
genetic variants at 91 risk loci. To systematically screen these variants for allelic …
[HTML][HTML] Autoimmunity-related risk variants in PTPN22 and CTLA4 are associated with ME/CFS with infectious onset
S Steiner, SC Becker, J Hartwig, F Sotzny… - Frontiers in …, 2020 - frontiersin.org
Single nucleotide polymorphisms (SNP) in various genes have been described to be
associated with susceptibility to autoimmune disease. In this study, myalgic …
associated with susceptibility to autoimmune disease. In this study, myalgic …
Strong association of combined genetic deficiencies in the classical complement pathway with risk of systemic lupus erythematosus and primary Sjögren's syndrome
C Lundtoft, C Sjöwall… - Arthritis & …, 2022 - Wiley Online Library
Objective Complete genetic deficiency of the complement component C2 is a strong risk
factor for monogenic systemic lupus erythematosus (SLE), but whether heterozygous C2 …
factor for monogenic systemic lupus erythematosus (SLE), but whether heterozygous C2 …
Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
Objective Copy number variation of the C4 complement components, C4A and C4B, has
been associated with systemic inflammatory autoimmune diseases. This study was …
been associated with systemic inflammatory autoimmune diseases. This study was …
[HTML][HTML] Impact of C4 , C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus
KMC Pereira, S Perazzio, AGA Faria… - Advances in …, 2019 - SciELO Brasil
Abstract Background Complement component 4 (C4) gene copy number (GCN) affects the
susceptibility to systemic lupus erythematosus (SLE) in different populations, however the …
susceptibility to systemic lupus erythematosus (SLE) in different populations, however the …
Albumin to globulin ratio (AGR) in systemic lupus erythematosus: correlation with disease activity
M Liu, X Li, Y Huang, Z Huang… - Journal of International …, 2024 - journals.sagepub.com
Objective To investigate the role of albumin-to-globulin ratio (AGR) in systemic lupus
erythematosus (SLE) and its relationship with disease activity. Methods This retrospective …
erythematosus (SLE) and its relationship with disease activity. Methods This retrospective …
Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis
Z Wu, S Zhang, P Li, F Zhang, Y Li - Clinical and Experimental Medicine, 2020 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by
multiple genetic mutations. Complement 4 (C4) copy number variation (CNV) is a target-of …
multiple genetic mutations. Complement 4 (C4) copy number variation (CNV) is a target-of …
The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders
The complement system, including complement components 3 and 4 (C3, C4), traditionally
has been linked to innate immunity. More recently, complement components have also been …
has been linked to innate immunity. More recently, complement components have also been …
Genome-wide discovery of SLE genetic risk variant allelic enhancer activity
Genome-wide association studies of Systemic Lupus Erythematosus (SLE) nominate 3,073
genetic variants at 91 risk loci. To systematically screen these variants for allelic …
genetic variants at 91 risk loci. To systematically screen these variants for allelic …
[HTML][HTML] Expression of C1q in the serum of patients with non‑severe aplastic anemia, and its association with disease severity
S Ding, C Liu, Y Li, H Liu, Z Liu… - Molecular …, 2019 - spandidos-publications.com
A type of aplastic anemia (AA), non-severe aplastic anemia (NSAA) is defined as AA that
does not meet the diagnostic criteria of severe aplastic anemia (SAA). Complement …
does not meet the diagnostic criteria of severe aplastic anemia (SAA). Complement …