Oridonin, as a natural terpenoids found in traditional Chinese herbal medicine Isodon
rubescens (Hemsl.) H. Hara, is widely present in numerous Chinese medicine preparations …

Cancer is one of the diseases with high morbidity and mortality on a global scale.
Chemotherapy remains the primary treatment option for most cancer patients, including …

Natural products have historically been, and continue to be, an invaluable source for the
discovery of various therapeutic agents. Oridonin, a natural diterpenoid widely applied in …

Natural products (NPs) have played a key role in drug discovery and are still a prolific
source of novel lead compounds or pharmacophores for medicinal chemistry …

Oridonin, a diterpenoid natural product commonly used in East Asian herbal medicine, is
garnering increased attention in the biomedical community due to its extensive biological …

Inflammation plays a pivotal role in the development and progression of diabetic
nephropathy (DN). Oridonin (Ori), a component isolated from Rabdosia rubescens …

Oridonin, an active diterpenoid isolated from Rabdosia rubescens, has been reported for its
antitumor activity on several cancers. However, its effect on human esophageal cancer …

The cytotoxicity of the natural ent-kaurene diterpenoid, oridonin, has been extensively
studied. However, the application of oridonin for cancer therapy was hampered primarily by …

The rapid increase of obesity rates worldwide is associated with chronic liver injury due to
non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Chronic liver …

Cancer is a leading cause of mortality responsible for an estimated 10 million deaths
worldwide in 2020, and its incidence has been rapidly growing over the last decades …