Pathogenesis, epidemiology and control of Group A Streptococcus infection

S Brouwer, T Rivera-Hernandez, BF Curren… - Nature Reviews …, 2023 - nature.com
Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

A systematic framework for prioritizing burden of disease data required for vaccine development and implementation: the case for group A streptococcal diseases

HC Moore, JW Cannon, DC Kaslow… - Clinical Infectious …, 2022 - academic.oup.com
Vaccine development and implementation decisions need to be guided by accurate and
robust burden of disease data. We developed an innovative systematic framework outlining …

Global economic burden per episode for multiple diseases caused by group A Streptococcus

JS Lee, S Kim, JL Excler, JH Kim, V Mogasale - npj Vaccines, 2023 - nature.com
Considering the lack of existing evidence on economic burden for diseases caused by
group A Streptococcus, we estimated the economic burden per episode for selected …

Modeling the potential health impact of prospective Strep A vaccines

F Giannini, JW Cannon, D Cadarette, DE Bloom… - npj Vaccines, 2023 - nature.com
Abstract The World Health Organization published the preferred product characteristics for a
Group A Streptococcus (Strep A) vaccine in 2018. Based on these parameters for the age of …

Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections

AL Whitcombe, R McGregor, J Bennett… - The Journal of …, 2022 - academic.oup.com
Abstract Background Group A Streptococcus (GAS) causes superficial pharyngitis and skin
infections as well as serious autoimmune sequelae such as acute rheumatic fever (ARF) …

[HTML][HTML] Global disease burden of Streptococcus pyogenes

N Craik, T Hla, J Cannon, H Moore… - … : Basic Biology to …, 2022 - ncbi.nlm.nih.gov
Methods We previously conducted a systematic review with the goal of including population-
based data published between 2005 and October 2014. We have now updated our review …

Development of a lateral flow immunoassay using antibody cocktail for the detection of the various epidemic subtypes of group A Streptococcus in clinical samples

B Peng, J Liang, Y Wang, G He, X Zhang, C Lu… - Sensors and Actuators B …, 2022 - Elsevier
Abstract Group A Streptococcus (GAS), a major pathogen, causes various respiratory
diseases with substantial morbidity and mortality worldwide. In this study, we develop an …

An eight-plex immunoassay for Group A streptococcus serology and vaccine development

AL Whitcombe, F Han, SM McAlister… - Journal of …, 2022 - Elsevier
Abstract Group A Streptococcus (GAS) is a major human pathogen responsible for
superficial infections through to life-threatening invasive disease and the autoimmune …

C10Pred: A first machine learning based tool to predict C10 family cysteine peptidases using sequence-derived features

A Malik, N Mahajan, TA Dar, CB Kim - International Journal of Molecular …, 2022 - mdpi.com
Streptococcus pyogenes, or group A Streptococcus (GAS), a gram-positive bacterium, is
implicated in a wide range of clinical manifestations and life-threatening diseases. One of …

Antibiotics or Tonsillectomy for Adult Recurrent Tonsillitis: Analyzing the Lesser of Two Evils

T Jacob, M Leshno, NN Carmel‐Neidermann… - The …, 2024 - Wiley Online Library
Objective To determine the best timing for surgical intervention for adults with recurrent
tonsillitis (RT). Methods A Markov model was constructed using variables and ranges based …