The increasing life expectancy of humans has led to a growing numbers of patients with
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …

There is a critical shortage in the number of deceased human organs that become available
for the purposes of clinical transplantation. This problem might be resolved by the …

Transplantation is often the last resort for end-stage organ failures, eg, kidney, liver, heart,
lung, and pancreas. The shortage of donor organs is the main limiting factor for successful …

▪ Abstract The increasing shortage of human cadaveric organs for purposes of
transplantation has become the critical limiting factor in the number of transplants performed …

The immunologic barriers to successful xenotransplantation are related to the presence of
natural anti‐pig antibodies in humans and non‐human primates that bind to antigens …

Background. The aims of this study were to evaluate the efficacy of US Food and Drug
Administration-approved drugs in genetically engineered pig-to-baboon kidney …

The discrepancy between organ need and organ availability represents one of the major
limitations in the field of transplantation. One possible solution to this problem is …

Transplantation is an effective approach for treating end-stage organ failure. There has been
a long-standing interest in xenotransplantation as a means of increasing the number of …

Background The pig‐to‐non‐human primate model is the standard choice for in vivo studies
of organ and cell xenotransplantation. In 1998, Lambrigts and his colleagues surveyed the …

Xenotransplantation has the potential to solve the shortfall of human organ donors.
Genetically modified pigs have been considered as potential animal donors for human …