Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver …
Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …
physiological processes including signal transduction, cellular metabolism and tissue …
Functional behavior of DHA and EPA in the formation of babies brain at different stages of age, and protect from different brain-related diseases
W Khalid, P Gill, MS Arshad, A Ali… - … Journal of Food …, 2022 - Taylor & Francis
Omega-3 fatty acids are rich in marine animals and plant-based foods like grains and seeds.
Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) are directly present in …
Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) are directly present in …
The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
Interactions between the gut microbial ecosystem and host lipid homeostasis are highly
relevant to host physiology and metabolic diseases. We present a comprehensive multi …
relevant to host physiology and metabolic diseases. We present a comprehensive multi …
Peroxisome proliferator‐activated receptor alpha target genes
The peroxisome proliferator‐activated receptor alpha (PPARα) is a ligand‐activated
transcription factor involved in the regulation of a variety of processes, ranging from …
transcription factor involved in the regulation of a variety of processes, ranging from …
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
H Guillou, D Zadravec, PGP Martin… - Progress in lipid research, 2010 - Elsevier
In mammalian cells, elongases and desaturases play critical roles in regulating the length
and degree of unsaturation of fatty acids and thereby their functions and metabolic fates. In …
and degree of unsaturation of fatty acids and thereby their functions and metabolic fates. In …
Alpha-linolenic acid and its conversion to longer chain n− 3 fatty acids: Benefits for human health and a role in maintaining tissue n− 3 fatty acid levels
G Barceló-Coblijn, EJ Murphy - Progress in lipid research, 2009 - Elsevier
There is little doubt regarding the essential nature of alpha-linolenic acid (ALA), yet the
capacity of dietary ALA to maintain adequate tissue levels of long chain n− 3 fatty acids …
capacity of dietary ALA to maintain adequate tissue levels of long chain n− 3 fatty acids …
ChREBP-mediated regulation of lipid metabolism: involvement of the gut microbiota, liver, and adipose tissue
Carbohydrate response element-binding protein (ChREBP) plays an important role in the
development of type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease, as well …
development of type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease, as well …
α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation
Abstract α-Linolenic acid (ALA), a carboxylic acid with 18 carbons and three cis double
bonds, is an essential fatty acid needed for human health and can be acquired via regular …
bonds, is an essential fatty acid needed for human health and can be acquired via regular …
Fatty acid elongases in mammals: their regulation and roles in metabolism
A Jakobsson, R Westerberg, A Jacobsson - Progress in lipid research, 2006 - Elsevier
A significant amount of the fatty acids synthesized by the cytosolic enzyme complex fatty acid
synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids …
synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids …
[HTML][HTML] Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain?
AF Domenichiello, AP Kitson, RP Bazinet - Progress in lipid research, 2015 - Elsevier
Docosahexaenoic acid (DHA) is important for brain function, and can be obtained directly
from the diet or synthesized in the body from α-linolenic acid (ALA). Debate exists as to …
from the diet or synthesized in the body from α-linolenic acid (ALA). Debate exists as to …