Non-alcoholic fatty liver disease (NAFLD) is a common long-lasting liver disease that affects
millions of people around the world. It is best identified with a hepatic fat build-up that …

Results Weight loss≥ 7–10% is central to lifestyle management; however, liver and
cardiometabolic benefits are attainable with improved diet quality and exercise even without …

Conclusions: Most guidelines recommend weight reduction through physical activity and
improving nutrition, as these have proven positive effects on health outcomes when …

BACKGROUND: Metabolic dysfunction–associated fatty liver disease is a significant risk
factor for cardiovascular disease (CVD). This study assesses the association between …

Chronic liver disease is a significant global health problem. Epidemiological trends do not
show improvement in chronic liver disease incidence but rather a shift in etiologies, with …

Fat is a “double-edged sword”: while it is a necessary substance for the body, the long-term
intake of excessive fat will cause obesity, with the liver subjected to lipotoxicity as it …

Metformin was developed from an offshoot of Guanidine. It is known to be the first-line
medication for type 2 diabetes mellitus, polycystic ovarian syndrome, and weight reduction …

Metabolic-associated fatty liver disease (MAFLD) includes several metabolic dysfunctions
caused by dysregulation in the brain–gut–liver axis and, consequently, increases …

Liver diseases contribute to approximately 2 million deaths each year and account for 4% of
all deaths globally. Despite various treatment options, the management of liver diseases …

Introduction The incidence of steatotic liver disease has increased in recent years. Thus,
steatotic liver disease is a major public health issue in Japan. This study investigated the …