This article summarizes the presentations given at an ESPEN Workshop on “Lipids in the
ICU” held in Tel Aviv, Israel in November 2014 and subsequent discussions and updates …

Hypoxic–ischemic brain damage is an alarming health and economic problem in spite of the
advances in neonatal care. It can cause mortality or detrimental neurological disorders such …

Intrapartum hypoxia–ischemia leading to neonatal encephalopathy (NE) results in
significant neonatal mortality and morbidity worldwide, with> 85% of cases occurring in low …

Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-
unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in …

White matter injury induced by ischemic stroke elicits sensorimotor impairments, which can
be further deteriorated by persistent proinflammatory responses. We previously reported that …

Brain development is a highly orchestrated complex process. The developing brain utilizes
many substrates including glucose, ketone bodies, lactate, fatty acids and amino acids for …

Background and Purpose Treatment with triglyceride emulsions of docosahexaenoic acid (tri-
DHA) protected neonatal mice against hypoxia-ischemia (HI) brain injury. The mechanism of …

Background: Preterm infants are at high risk for Encephalopathy of Prematurity and
successive adverse neurodevelopmental outcome. Adequate nutrition is crucial for healthy …

Stroke is a devastating neurological disorder that is characterized by the sudden disruption
of blood flow to the brain. Lipids are essential components of brain structure and function …

Fatty acids are critical nutrient regulators of intracellular signaling and influence key
pathways including inflammatory responses, hemostasis as well as central nervous system …