The aminoacyl-tRNA synthetases are an essential and universally distributed family of
enzymes that plays a critical role in protein synthesis, pairing tRNAs with their cognate …

RNA motifs are directed and ordered stacked arrays of non-Watson–Crick base pairs
forming distinctive foldings of the phosphodiester backbones of the interacting RNA strands …

1. Introduction 2222. What is an RNA motif? 2222.1 Sequence vs. structural motifs 2222.2
RNA structural motifs 2232.3 RNA structural elements vs. motifs 2232.4 Specific recognition …

The occurrences of two recurrent motifs in ribosomal RNA sequences, the Kink-turn and the
C-loop, are examined in crystal structures and systematically compared with sequence …

The accurate synthesis of proteins, dictated by the corresponding nucleotide sequence
encoded in mRNA, is essential for cell growth and survival. Central to this process are the …

We have identified a highly conserved RNA motif located upstream of genes encoding
molybdate transporters, molybdenum cofactor (Moco) biosynthesis enzymes, and proteins …

The trend toward designing large hydrophobic molecules for lead optimization is often
associated with poor drug-likeness and high attrition rates in drug discovery and …

RNA binding proteins are capable of regulating translation initiation by a variety of
mechanisms. Although the vast majority of these regulatory mechanisms involve …

Aminoacyl-tRNA synthetases (aaRS) are the enzymes that ensure faithful transmission of
genetic information in all living cells, and are central to the developing technologies for …

A fundamental question in biology is how vertebrates evolved and differ from invertebrates,
and little is known about differences in the regulation of translation in the two systems …