Cysteine dioxygenases, 3‐mercaptopropionate dioxygenases and mercaptosuccinate
dioxygenases are all thiol dioxygenases (TDOs) that catalyse oxidation of thiol molecules to …

Here, the choice of the first coordination shell of the metal center is analyzed from the
perspective of charge maintenance in a binary enzyme–substrate complex and an O2 …

Background A high content in anthocyanins, for their health beneficial properties, represents
an added value for fruits and vegetables. Tomato (Solanum lycopersicum) is one of the most …

Cys is one of the least abundant amino acids in proteins. However, it is often highly
conserved and is usually found in important structural and functional regions of proteins. Its …

Plant cysteine oxidases (PCOs) are plant O2‐sensing enzymes. They catalyse the O2‐
dependent step which initiates the proteasomal degradation of Group VII ethylene response …

Cysteamine dioxygenase (ADO) plays a vital role in regulating thiol metabolism and
preserving oxygen homeostasis in humans by oxidizing the sulfur of cysteamine and N …

All aerobic organisms require O2 for survival. When their O2 is limited (hypoxia), a response
is required to reduce demand and/or improve supply. A hypoxic response mechanism has …

Plant Cysteine Oxidase (PCO) is a plant O2-sensing enzyme catalyzing the oxidation of
cysteine to Cys-sulfinic acid at the N-termini of target proteins. To better understand the …

Hypoxic responses in plants involve Plant Cysteine Oxidases (PCOs). They catalyze the N-
terminal cysteine oxidation of Ethylene Response Factors VII (ERF-VII) in an oxygen …

Abstract Plant Cysteine Oxidase (PCO) is a plant O2-sensing enzyme of catalyzing oxidation
of cysteine to Cys-sulfinic acid at the N-termini of target proteins. To better understand the …