Mycobacteriophages as potential therapeutic agents against drug-resistant tuberculosis

A Allué-Guardia, R Saranathan, J Chan… - International journal of …, 2021 - mdpi.com
The current emergence of multi-, extensively-, extremely-, and total-drug resistant strains of
Mycobacterium tuberculosis poses a major health, social, and economic threat, and stresses …

Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review

F Zeynali kelishomi, S Khanjani, F Fardsanei… - BMC Infectious …, 2022 - Springer
Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly
infectious disease and worldwide health problem. Based on the WHO TB report, 9 million …

Identification of a new antiphage system in Mycobacterium phage Butters

HT Mohammed, C Mageeney, VC Ware - bioRxiv, 2023 - biorxiv.org
During lysogeny temperate phages establish a truce with the bacterial host. In this state, the
phage genome (prophage) is maintained within the host environment. Consequently, many …

Characterization of novel recombinant mycobacteriophages derived from homologous recombination between two temperate phages

HT Mohammed, C Mageeney… - G3: Genes …, 2023 - academic.oup.com
Comparative analyses of mycobacteriophage genomes reveals extensive genetic diversity
in genome organization and gene content, contributing to widespread mosaicism. We …

Elucidating Mechanisms of Mycobacteriophage Butters Prophage-Mediated Defenses

HT Mohammed - 2023 - search.proquest.com
Many bacterial genomes contain prophages that may act to modulate host physiology.
Prophages that bolster host immunity against viral infection could challenge the …