Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges

M Arenas‐Jal, JM Suñé‐Negre… - … reviews in food …, 2020 - Wiley Online Library
World population growth and aging are posing unprecedented challenges in sustaining the
health of 9.1 billion people that will be occupying the planet by 2050. Although …

Microencapsulation of bioactives for food applications

MI Dias, ICFR Ferreira, MF Barreiro - Food & function, 2015 - pubs.rsc.org
Health issues are an emerging concern to the world population, and therefore the food
industry is searching for novel food products containing health-promoting bioactive …

[HTML][HTML] Cavitation technology–a greener processing technique for the generation of pharmaceutical nanoemulsions

M Sivakumar, SY Tang, KW Tan - Ultrasonics sonochemistry, 2014 - Elsevier
Novel nanoemulsion-based drug delivery systems (DDS) have been proposed as
alternative and effective approach for the delivery of various types of poorly water-soluble …

Novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of olmesartan medoxomil: design, formulation, pharmacokinetic and …

A Nasr, A Gardouh, M Ghorab - Pharmaceutics, 2016 - mdpi.com
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …

Oral formulation strategies to improve solubility of poorly water-soluble drugs

A Singh, ZA Worku… - Expert opinion on drug …, 2011 - Taylor & Francis
Introduction: In the past two decades, there has been a spiraling increase in the complexity
and specificity of drug–receptor targets. It is possible to design drugs for these diverse …

Controversies with self-emulsifying drug delivery system from pharmacokinetic point of view

B Chatterjee, S Hamed Almurisi… - Drug …, 2016 - Taylor & Francis
Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and
co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium …

Coenzyme Q10 effects in neurodegenerative disease

M Spindler, MF Beal, C Henchcliffe - Neuropsychiatric disease and …, 2009 - Taylor & Francis
Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial respiratory chain, and
as a dietary supplement it has recently gained attention for its potential role in the treatment …

Multifunctional iron bound lactoferrin and nanomedicinal approaches to enhance its bioactive functions

JR Kanwar, K Roy, Y Patel, SF Zhou, MR Singh… - Molecules, 2015 - mdpi.com
Lactoferrin (Lf), an iron-binding protein from the transferrin family has been reported to have
numerous functions. Even though Lf was first isolated from milk, it is also found in most …

Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs

P Tran, JS Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …