The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P),
produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the glycolytic …

Metformin is a well-known anti-diabetic drug that has been repurposed for several emerging
applications, including as an anti-cancer agent. It boasts the distinct advantages of an …

Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Physical activity has been associated with lower risks of breast and colorectal cancer in
epidemiological studies; however, it is unknown if these associations are causal or …

Palmitic acid (PA) has been for long time negatively depicted for its putative detrimental
health effects, shadowing its multiple crucial physiological activities. PA is the most common …

Background Despite the rising popularity of plant-based alternative meats, there is limited
evidence of the health effects of these products. Objectives We aimed to compare the effect …

Background: Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of
developing several common cancers, but it is unclear whether this association is causal. We …

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Over the past decade, the search for dietary factors on which to base cancer prevention
guidelines has led to the rapid expansion of the field of dietary patterns and cancer. Multiple …

Lung cancer remains the leading cause of cancer mortality in men and women in the US
and worldwide. About 90% of lung cancer cases are caused by smoking and the use of …