Evaluating the hazardous impact of ionic liquids–challenges and opportunities

S Magina, A Barros-Timmons, SPM Ventura… - Journal of Hazardous …, 2021 - Elsevier
Ionic liquids (ILs), being related to the design of new environmentally friendly solvents, are
widely considered for applications within the “green chemistry” concept. Due to their unique …

Mechanisms of action of ionic liquids on living cells: The state of the art

P Kumari, VVS Pillai, A Benedetto - Biophysical reviews, 2020 - Springer
Ionic liquids (ILs) are a relatively new class of organic electrolytes composed of an organic
cation and either an organic or inorganic anion, whose melting temperature falls around …

Fundamental importance of ionic interactions in the liquid phase: A review of recent studies of ionic liquids in biomedical and pharmaceutical applications

KS Egorova, VP Ananikov - Journal of Molecular Liquids, 2018 - Elsevier
In recent years, research on ions and ionic interactions in solution has become a leading
scientific direction, and this advance has been especially pronounced in the field of ionic …

[HTML][HTML] Imidazolium-based ionic liquids cause mammalian cell death due to modulated structures and dynamics of cellular membrane

K Bakshi, S Mitra, VK Sharma, MSK Jayadev… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Here, we report the toxic effects of various imidazolium-based ionic liquids (ILs) with varying
hydrocarbon chain lengths, on different human cell lines. Multiple biological assays have …

Understanding the structure and dynamics of complex biomembrane interactions by neutron scattering techniques

S Qian, VK Sharma, LA Clifton - Langmuir, 2020 - ACS Publications
The membrane is one of the key structural materials of biology at the cellular level.
Composed predominantly of a bilayer of lipids with embedded and bound proteins, it defines …

Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

Cholesterol-controlled interaction of ionic liquids with model cellular membranes

P Hitaishi, M Raval, A Seth, S Kumar, VS Mithu… - Langmuir, 2023 - ACS Publications
While ionic liquids (ILs) are considered as prospective ingredients of new antimicrobial
agents, it is important to understand the adverse effects of these molecules on human cells …

Cholesterol protects the liquid-ordered phase of raft model membranes from the destructive effect of ionic liquids

XL Hao, B Cao, D Dai, FG Wu… - The Journal of Physical …, 2022 - ACS Publications
Ionic liquids (ILs), although being a class of promising green solvents, have received many
reports on the toxicity to living organisms. In this work, aiming at elucidating the disruptive …

The Physics of Antimicrobial Activity of Ionic Liquids

VK Sharma, J Gupta, JB Mitra… - The Journal of …, 2024 - ACS Publications
The bactericidal potency of ionic liquids (ILs) is well-established, yet their precise
mechanism of action remains elusive. Here, we show evidence that the bactericidal action of …

[HTML][HTML] Recent perspectives on microbial and ionic liquid interactions with implications for biorefineries

J Grewal, SK Khare, L Drewniak, K Pranaw - Journal of Molecular Liquids, 2022 - Elsevier
In recent years, in pursuit of sustainable and green chemistry, a plethora of ionic liquids (ILs)
have been formulated to serve as safe alternatives to toxic solvents for numerous …