Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …

ABSTRACT “A journey of mixed emotions” is a quote that best describes the progress chart
of vascular endothelial growth factor receptor (VEGFR) inhibitors as cancer therapeutics in …

Two series of pyrazoline compounds were designed and synthesized as antiproliferative
agents by VEGFR pathway inhibition. All synthesized compounds were screened by the …

Herein, the synthesis and characterization of a triazine-based magnetic ionic porous organic
polymer are reported. The structure, morphology, and components of the prepared structure …

This study demonstrates that the purified β-glucan (LNT) with a triple helix and relatively
narrow molecular weight distribution, extracted and purified from artificially cultured Lentinus …

Ethanol volume fraction of 80% was widely applied for polysaccharides precipitation from
Codonopsis pilosula water-leach liquor, while few researches focused on the dissolved …

The biological activity of amorphous selenium nanoparticles (SeNPs) was limited by their
poor stability and rapid spontaneous phase transformation. Herein, we prepared amorphous …

In the present study, a drug-like molecular hybrid structure between chalcone and
sulfonamide moieties was synthesized and characterized. The structural peculiarities of the …

Many studies have been carried out to find synthetic pathways to nicotinonitriles (3-
cyanopyridines) and their analogs, which has resulted in a substantial amount of knowledge …

The overexpression of EGFR has been recognized as the driver mechanism in the
development of several human malignancies and the clinical use of EGFR inhibitors …