Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …

Acute pancreatitis (AP), as a common cause of clinical acute abdomen, often leads to multi-
organ damage. In the process of severe AP, the lungs and intestines are the most easily …

Rationale Using latent class analysis (LCA), two subphenotypes of acute respiratory distress
syndrome (ARDS) have consistently been identified in five randomised controlled trials …

The host response to COVID-19 pathophysiology over the first few days of infection remains
largely unclear, especially the mechanisms in the blood compartment. We report on a …

Acute respiratory distress syndrome (ARDS) is a frequently encountered clinical syndrome
associated with unacceptably high morbidity and mortality. 1 Since its first description in …

No targeted therapies exist to counteract Hyperoxia (HO)-induced Acute Lung Injury (HALI).
We previously found that HO downregulates alveolar K2P2. 1 (TREK-1) K+ channels, which …

Introduction: Intrauterine adhesions (IUA), also known as Asherman's syndrome, is caused
by trauma to the pregnant or non-pregnant uterus, which leads to damaged endometrial …

Background: Matrix Metalloproteinases (MMP) respond to tissue damage during sepsis.
Higher plasma concentrations of MMPs and the tissue-inhibitor of matrix metalloproteinases …

Lipopolysaccharide (LPS)-induced autophagy inhibition in lung fibroblasts is closely
associated with the activation of the phosphatidylinositol 3-kinase/protein kinase …

Background Acute respiratory distress syndrome (ARDS) is heterogeneous and may be
amenable to sub-phenotyping to improve enrichment for trials. We aimed to identify …