[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

J Barrera‐Chimal, F Jaisser - Diabetes, Obesity and …, 2020 - Wiley Online Library
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway

Q Li, J Liao, W Chen, K Zhang, H Li, F Ma… - Free Radical Biology …, 2022 - Elsevier
Diabetic nephropathy (DN) is known as a major microvascular complication in type 1
diabetes. The effect of insulin treatment alone on controlling blood glucose is unsatisfactory …

[HTML][HTML] Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3

HJ Sun, SP Xiong, X Cao, L Cao, MY Zhu, ZY Wu… - Redox biology, 2021 - Elsevier
Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …

Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

YQ Chen, HY Chen, QQ Tang, YF Li, XS Liu… - Frontiers in …, 2022 - frontiersin.org
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but
effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely …

Hyperhomocysteinemia and cardiovascular disease: is the adenosinergic system the missing link?

F Paganelli, G Mottola, J Fromonot, M Marlinge… - International journal of …, 2021 - mdpi.com
The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains
unclear. HHCy is associated with inflammation and atherosclerosis, and it is an independent …

Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway

Y Wen, Y Liu, Q Huang, R Liu, J Liu, F Zhang, S Liu… - Phytomedicine, 2022 - Elsevier
Abstract Background Moringa oleifera Lam.(M. oleifera) seeds are widely used in traditional
folk medicine and as nutritional supplements in the Middle East, Africa, and other regions …

Hydrogen sulfide reduces pyroptosis and alleviates ischemia-reperfusion-induced acute kidney injury by inhibiting NLRP3 inflammasome

J Ni, L Jiang, G Shen, Z Xia, L Zhang, J Xu, Q Feng… - Life Sciences, 2021 - Elsevier
Abstract Aims Ischemia-reperfusion (I/R)-induced acute kidney injury (AKI) shows high
mortality. Hydrogen sulfide (H 2 S) is essential for regulating kidney function. This study …

[HTML][HTML] Implications of hydrogen sulfide in liver pathophysiology: Mechanistic insights and therapeutic potential

HJ Sun, ZY Wu, XW Nie, XY Wang, JS Bian - Journal of advanced research, 2021 - Elsevier
Background Over the last several decades, hydrogen sulfide (H 2 S) has been found to exert
multiple physiological functions in mammal systems. The endogenous production of H 2 S is …

Fighting oxidative stress with sulfur: Hydrogen sulfide in the renal and cardiovascular systems

JJ Scammahorn, ITN Nguyen, EM Bos, H Van Goor… - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S) is an essential gaseous signaling molecule. Research on its role in
physiological and pathophysiological processes has greatly expanded. Endogenous …