Neutrophils at the crossroads of innate and adaptive immunity

C Rosales - Journal of Leucocyte Biology, 2020 - academic.oup.com
Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly
mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display …

[HTML][HTML] Update on neutrophil function in severe inflammation

E Mortaz, SD Alipoor, IM Adcock, S Mumby… - Frontiers in …, 2018 - frontiersin.org
Neutrophils are main players in the effector phase of the host defense against micro-
organisms and have a major role in the innate immune response. Neutrophils show …

Fluorescence-amplified nanocrystals in the second near-infrared window for in vivo real-time dynamic multiplexed imaging

Y Yang, Y Chen, P Pei, Y Fan, S Wang, H Zhang… - Nature …, 2023 - nature.com
Optical imaging in the second near-infrared window (NIR-II, 1,000–1,700 nm) holds great
promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging …

[PDF][PDF] Leukocyte migration into inflamed tissues

S Nourshargh, R Alon - Immunity, 2014 - cell.com
Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …

Neutrophils at work

WM Nauseef, N Borregaard - Nature immunology, 2014 - nature.com
In this Review we discuss data demonstrating recently recognized aspects of neutrophil
homeostasis in the steady state, granulopoiesis in'emergency'conditions and interactions of …

[HTML][HTML] LFA-1 in T cell migration and differentiation

BL Walling, M Kim - Frontiers in immunology, 2018 - frontiersin.org
Maintenance of homeostatic immune surveillance and development of effective adaptive
immune responses require precise regulation of spatial and temporal lymphocyte trafficking …

The multifaceted functions of neutrophils

TN Mayadas, X Cullere… - Annual Review of …, 2014 - annualreviews.org
Neutrophils and neutrophil-like cells are the major pathogen-fighting immune cells in
organisms ranging from slime molds to mammals. Central to their function is their ability to …

Neutrophil trails guide influenza-specific CD8+ T cells in the airways

K Lim, YM Hyun, K Lambert-Emo, T Capece, S Bae… - Science, 2015 - science.org
INTRODUCTION Influenza virus infects the epithelial cells that line the respiratory tract.
Therefore, cytotoxic CD8+ T cells must traffic to this site to eliminate infected cells. The …

Neutrophil transendothelial migration: updates and new perspectives

MD Filippi - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
Neutrophils represent the first line of cellular defense against invading microorganism by
rapidly moving across the blood–endothelial cell (EC) barrier and exerting effector cell …

Getting leukocytes to the site of inflammation

WA Muller - Veterinary pathology, 2013 - journals.sagepub.com
There is no “response” in either the innate or adaptive immune response unless leukocytes
cross blood vessels. They do this through the process of diapedesis, in which the leukocyte …