[HTML][HTML] Ebselen and analogues: Pharmacological properties and synthetic strategies for their preparation
C Santi, C Scimmi, L Sancineto - Molecules, 2021 - mdpi.com
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
Synthesis and antioxidant properties of organoselenium compounds
Background: The chemistry of organoselenium reagents provides an asset for organic
synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them …
synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them …
[HTML][HTML] Recent advances in the synthesis and antioxidant activity of low molecular mass organoselenium molecules
JM Anghinoni, PT Birmann, MJ da Rocha, CS Gomes… - Molecules, 2023 - mdpi.com
Selenium is an essential trace element in living organisms, and is present in selenoenzymes
with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) …
with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) …
Iodolopyrazolium salts: synthesis, derivatizations, and applications
A Boelke, TJ Kuczmera, LD Caspers, E Lork… - Organic …, 2020 - ACS Publications
The synthesis of iodolopyrazolium triflates via an oxidative cyclization of 3-(2-iodophenyl)-1
H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and …
H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and …
[HTML][HTML] Recent advances in the synthesis of selenophenes and their derivatives
The selenophene derivatives are an important class of selenium-based heterocyclics. These
compounds play an important role in prospecting new drugs, as well as in the development …
compounds play an important role in prospecting new drugs, as well as in the development …
Synthesis of 4-Selanyl- and 4-Tellanyl-1H-isochromen-1-ones Promoted by Diorganyl Dichalcogenides and Oxone
HA Goulart, JSS Neto, AM Barcellos… - The Journal of …, 2021 - ACS Publications
A new method was developed for the synthesis of 4-chalcogenyl-1 H-isochromen-1-ones
through the 6-endo-dig electrophilic cyclization of 2-alkynylaryl esters and diorganyl …
through the 6-endo-dig electrophilic cyclization of 2-alkynylaryl esters and diorganyl …
Introduction of methyl group in substituted isoselenazolones: catalytic and mechanistic study
M Kumar, B Chhillar, D Verma, S Nain… - The Journal of Organic …, 2023 - ACS Publications
Copper-catalyzed direct selenation of substituted 2-bromo-N-phenylbenzamide substrates
with elemental selenium powder provided a series of methoxy-substituted isoselenazolones …
with elemental selenium powder provided a series of methoxy-substituted isoselenazolones …
Catalytic and highly regenerable aminic organoselenium antioxidants with cytoprotective effects
Novel N-methylated ebselenamine antioxidants were prepared from the corresponding
diselenides with iodomethane. All ebselenamines showed excellent chain-breaking and …
diselenides with iodomethane. All ebselenamines showed excellent chain-breaking and …
A novel methodology for the synthesis of condensed selenium heterocycles based on the annulation and annulation–methoxylation reactions of selenium dihalides
MV Musalov, VA Yakimov, VA Potapov… - New Journal of …, 2019 - pubs.rsc.org
A novel methodology to accelerate annulation reactions leading to condensed selenium
heterocycles was developed. The reactions of selenium dihalides with methyleugenol, allyl …
heterocycles was developed. The reactions of selenium dihalides with methyleugenol, allyl …
Synthesis and antioxidant activities of N-thiophenyl ebselenamines: a 77 Se {1 H} NMR mechanistic study
The step-by-step redox process of bis-[2-phenyl-1, 2-benzisoselenazol-3 (2H)-one-7-yl]
diazene ie azo-bis-ebselen in the presence of PhSH and H2O2 was reported using 77Se …
diazene ie azo-bis-ebselen in the presence of PhSH and H2O2 was reported using 77Se …