Fracture risk is increased in patients with type 2 diabetes mellitus (T2DM). In addition, these
patients sustain fractures despite having higher levels of areal bone mineral density, as …

Advanced glycation end products (AGEs) are formed as a result of non-enzymatic reaction
between the free reducing sugars and proteins, lipids, or nucleic acids. AGEs are …

The receptor for advanced glycation end-products (RAGE) was initially characterized and
named for its ability to bind to advanced glycation end-products (AGEs) that form upon the …

Oxidative stress (OS)‐induced mitochondrial damage and the subsequent osteoblast
dysfunction contributes to the initiation and progression of osteoporosis. Notoginsenoside …

Mitochondria are important organelles that provide cellular energy and play a vital role in
cell differentiation and apoptosis. Osteoporosis is a chronic metabolic bone disease mainly …

Osteoporosis is an aging‐associated disease that is attributed to excessive osteoblast
apoptosis. It is known that the accumulation of advanced glycation end products (AGEs) in …

Sarcopenia is common in chronic kidney disease (CKD), and it is independently associated
with morbidity and mortality. Advanced glycation end products (AGE) are mainly known as …

Excessive generation of reactive oxygen species (ROS) have great impacts on the
development of periodontitis. Dynamin-related protein 1 (Drp1) mediated mitochondrial …

Mitochondrial dysfunction is critical in the pathogenesis of asthma. Mitochondrial
permeability transition pore (mPTP) regulates the release of mitochondrial damage …

Osteoblasts dysfunction, induced by oxidative stress (OS), is one of major pathological
mechanisms for osteoporosis. Curcumin (Cur), a bioactive antioxidant compound, isolated …