Rapid molecular diagnosis of live Mycobacterium tuberculosis on an integrated microfluidic system
CH Wang, JR Chang, SC Hung, HY Dou… - Sensors and Actuators B …, 2022 - Elsevier
Tuberculosis (TB) is a serious, potentially fatal disease that has been a global public health
issue for centuries. The growth of the causal bacterium Mycobacterium tuberculosis (M …
issue for centuries. The growth of the causal bacterium Mycobacterium tuberculosis (M …
Rapid molecular detection of multidrug-resistant tuberculosis by PCR-nucleic acid lateral flow immunoassay
H Kamphee, A Chaiprasert, T Prammananan… - PLoS …, 2015 - journals.plos.org
Several existing molecular tests for multidrug-resistant tuberculosis (MDR-TB) are limited by
complexity and cost, hindering their widespread application. The objective of this proof of …
complexity and cost, hindering their widespread application. The objective of this proof of …
Contribution of putative efflux pump genes to isoniazid resistance in clinical isolates of Mycobacterium tuberculosis
A Narang, A Giri, S Gupta, K Garima… - The International …, 2017 - journals.lww.com
Background: Isoniazid (INH) resistance in Mycobacterium tuberculosis has been mainly
attributed to mutations in katG (64%) and inhA (19%). However, 20%–30% resistance to INH …
attributed to mutations in katG (64%) and inhA (19%). However, 20%–30% resistance to INH …
Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes
Background Molecular epidemiological studies of Mycobacterium tuberculosis (MTB) are the
core of current research to find out the association of the M. tuberculosis genotypes with its …
core of current research to find out the association of the M. tuberculosis genotypes with its …
Detection of drug resistance in Mycobacterium tuberculosis: Methods, principles and applications
A Gupta, S Anupurba - indian journal of tuberculosis, 2015 - Elsevier
The growing emergence of multidrug resistant tuberculosis (MDR-TB) strains is obstructing
efforts for the control and management of TB. Proper management of MDR-TB relies on …
efforts for the control and management of TB. Proper management of MDR-TB relies on …
Tools to Alleviate the Drug Resistance in Mycobacterium tuberculosis
AA Rabaan, AA Mutair, H Albayat, J Alotaibi… - Molecules, 2022 - mdpi.com
Mycobacterium tuberculosis (Mtb), an acid-fast bacillus that causes Tuberculosis (TB), is a
pathogen that caused 1.5 million deaths in 2020. As per WHO estimates, another 4.1 million …
pathogen that caused 1.5 million deaths in 2020. As per WHO estimates, another 4.1 million …
Direct detection of rifampin and isoniazid resistance in sputum samples from tuberculosis patients by high-resolution melt curve analysis
D Anthwal, RK Gupta, M Bhalla… - Journal of clinical …, 2017 - Am Soc Microbiol
Drug-resistant tuberculosis (TB) is a major threat to TB control worldwide. Globally, only 40%
of the 340,000 notified TB patients estimated to have multidrug-resistant-TB (MDR-TB) were …
of the 340,000 notified TB patients estimated to have multidrug-resistant-TB (MDR-TB) were …
Utility of line probe assay in detecting drug resistance and the associated mutations in patients with extrapulmonary tuberculosis in Addis Ababa, Ethiopia
G Diriba, A Kebede, HH Tola, A Alemu… - SAGE Open …, 2022 - journals.sagepub.com
Introduction: Molecular tests allow rapid detection of Mycobacterium tuberculosis and drug
resistance in a few days. Identifying the mutations in genes associated with drug resistance …
resistance in a few days. Identifying the mutations in genes associated with drug resistance …
Codon usage divergence of important functional genes in Mycobacterium tuberculosis
G Li, L Zhang, P Xue - International Journal of Biological Macromolecules, 2022 - Elsevier
Sequence characteristics are usually used to explain the adaptive ability to hosts,
metabolism, genetic diversity, drug resistance, and infectivity of Mycobacterium tuberculosis …
metabolism, genetic diversity, drug resistance, and infectivity of Mycobacterium tuberculosis …
Frequency of Mutations Associated with Rifampicin Resistance in Mycobacterium tuberculosis Strains Isolated from Patients in West of Iran
P Mohajeri, H Sadri, A Farahani, B Norozi… - Microbial Drug …, 2015 - liebertpub.com
Background and Objective: Tuberculosis (TB) is a devastating infectious disease causing
high mortality and morbidity worldwide. The most serious threat related to tuberculosis …
high mortality and morbidity worldwide. The most serious threat related to tuberculosis …