Tuberculosis is a contagious disease with comparatively high mortality worldwide. The
statistics shows that around three million people throughout the world die annually from …

Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological
properties, which could play a major role in the common mechanisms associated with …

Indoleamine 2, 3-dioxygenase 1 (IDO1) is an important therapeutic target for the treatment of
diseases such as cancer that involve pathological immune escape. Starting from the scaffold …

Abstract Series of coordination complexes of Ni (II), Cu (II), Zn (II), Cd (II) and Sn (II) metal
with 4-amino-5-(pyridyl)-4H-1, 2, 4-triazole-3-thiol, as a ligand has been successfully …

A series of triazole conjugated novel 2, 5-diaryl 1, 3, 4-oxadiazole derivatives 8a-q are
efficiently synthesized starting from methyl salicylate. All the synthesized compounds were …

The 3-keto functionality in ring A of myrrhanone C, a natural bicyclic triterpene has been
chemically modified and synthesized 27 novel triazole hybrids belonging to two different …

A facile and convenient approach has been designed for the synthesis of novel prototypes
that possess the advantage of the two pharmacophores of chromene and 1, 2, 3-triazole in a …

New series of biologically active triazole and pyrazole compounds containing 2, 4-
disubstituted thiazole analogues (12a-l) were synthesized from p-hydroxy benzaldehyde …

Three series of novel heterocyclic compounds (3a–3g, 4a–4g and 5a–5g) containing
benzenesulfonamide moiety and incorporating a 1, 2, 4-triazole ring, have been synthesized …

A strategy for the efficient two-step synthesis of triazole derivatives of oxindoles and
spirooxindoles is presented. Using a common set of N-propargylated isatins, a series of …