Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Stroke is one of the leading causes of long-term disability among adults and contributes to
major socio-economic burden globally. Stroke frequently results in multifaceted impairments …

Neurological and mental illnesses account for a considerable proportion of the global
burden of disease. Exercise has many beneficial effects on brain health, contributing to …

Exercise promotes learning and memory formation. These effects depend on increases in
hippocampal BDNF, a growth factor associated with cognitive improvement and the …

Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

Physical exercise can convey a protective effect against cognitive decline in ageing and
Alzheimer's disease. While the long-term health-promoting and protective effects of exercise …

Background Numerous daily activities require simultaneous application of motor and
cognitive skills (dual-tasking). The execution of such tasks is especially difficult for the …

Exercise is known to induce a cascade of molecular and cellular processes that support
brain plasticity. Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin that is …