Catalysis in Pickering emulsions

AMB Rodriguez, BP Binks - Soft Matter, 2020 - pubs.rsc.org
Particle-stabilised or Pickering emulsions are versatile systems. In the past 10 years a new
application has emerged in the field of catalysis to use them as vehicles to carry out catalytic …

Cell‐inspired all‐aqueous microfluidics: from intracellular liquid–liquid phase separation toward advanced biomaterials

Q Ma, Y Song, W Sun, J Cao, H Yuan… - Advanced …, 2020 - Wiley Online Library
Living cells have evolved over billions of years to develop structural and functional
complexity with numerous intracellular compartments that are formed due to liquid–liquid …

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles

WM Aumiller Jr, CD Keating - Nature chemistry, 2016 - nature.com
Biological cells are highly organized, with numerous subcellular compartments.
Phosphorylation has been hypothesized as a means to control the assembly/disassembly of …

Liquid–liquid phase separation in artificial cells

CD Crowe, CD Keating - Interface Focus, 2018 - royalsocietypublishing.org
Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of
intracellular compartmentalization. Because the mechanisms driving phase separations are …

Bioreactor droplets from liposome-stabilized all-aqueous emulsions

DC Dewey, CA Strulson, DN Cacace… - Nature …, 2014 - nature.com
Artificial bioreactors are desirable for in vitro biochemical studies and as protocells. A key
challenge is maintaining a favourable internal environment while allowing substrate entry …

Experimental models for dynamic compartmentalization of biomolecules in liquid organelles: Reversible formation and partitioning in aqueous biphasic systems

WM Aumiller Jr, CD Keating - Advances in colloid and interface science, 2017 - Elsevier
Living cells contain numerous subcellular compartments, many of which lack membranous
boundaries and are thought to occur due to liquid–liquid phase coexistence. This review will …

Membraneless compartmentalization facilitates enzymatic cascade reactions and reduces substrate inhibition

T Kojima, S Takayama - ACS applied materials & interfaces, 2018 - ACS Publications
Living cells possess membraneless organelles formed by liquid–liquid phase separation.
With the aim of better understanding the general functions of membraneless …

Interactions of macromolecular crowding agents and cosolutes with small-molecule substrates: effect on horseradish peroxidase activity with two different substrates

WM Aumiller Jr, BW Davis, E Hatzakis… - The Journal of …, 2014 - ACS Publications
The importance of solution composition on enzymatic reactions is increasingly appreciated,
particularly with respect to macromolecular cosolutes. Macromolecular crowding and its …

Dynamic behavior of liquid droplets with enzyme compartmentalization triggered by sequential glycolytic enzyme reactions

T Ura, S Tomita, K Shiraki - Chemical Communications, 2021 - pubs.rsc.org
Dynamic droplet formation via liquid–liquid phase separation (LLPS) is believed to be
involved in the regulation of various biological processes. Here, a model LLPS system …

Biomolecular condensates regulate enzymatic activity under a crowded milieu: synchronization of liquid–liquid phase separation and enzymatic transformation

B Saini, TK Mukherjee - The Journal of Physical Chemistry B, 2023 - ACS Publications
Cellular crowding plays a key role in regulating the enzymatic reactivity in physiological
conditions, which is challenging to realize in the dilute phase. Enzymes drive a wide range …