Glioma is the most common type of primary CNS tumor, composed of cells that resemble
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …

Diffuse midline glioma-H3K27M mutant (DMG) and glioblastoma (GBM) are the most lethal
brain tumors that primarily occur in pediatric and adult patients, respectively. Both tumors …

Glioblastoma (GBM), classified as a grade IV glioma, is a rapidly growing, aggressive, and
most commonly occurring tumor of the central nervous system. Despite the therapeutic …

Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8%
of the human genome. Although normally silenced, the most recently integrated provirus …

Glioblastoma (GBM) tumors consist of multiple cell populations, including self-renewing
glioblastoma stem cells (GSCs) and immunosuppressive microglia. Here we identified …

Detecting and targeting precancerous cells in noncancerous tissues is a major challenge for
cancer prevention. Massive stabilization of mutant p53 (mutp53) proteins is a cancer-specific …

Background Resistance to temozolomide (TMZ) is a major obstacle to preventing
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …

Abstract Background Circular RNAs (circRNAs) have been shown to be essential for the
emergence and growth of different cancers. However, further research is required to validate …

With the application of high throughput sequencing technologies at single-cell resolution,
studies of the tumor microenvironment in glioblastoma, one of the most aggressive and …

Background: It is essential to develop better biomarkers for diagnosis, prediction, and
treating glioma patients to ensure successful clinical outcomes. The clinical application of …