The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Exosomes as messengers between mother and fetus in pregnancy

L Czernek, M Düchler - International Journal of Molecular Sciences, 2020 - mdpi.com
The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

The exosome: a review of current therapeutic roles and capabilities in human reproduction

M Dimik, P Abeysinghe, J Logan, M Mitchell - Drug Delivery and …, 2023 - Springer
Abstract Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …

Exosomes and exosomal non‑coding RNAs throughout human gestation

I Maligianni, C Yapijakis, K Nousia… - Experimental and …, 2022 - spandidos-publications.com
In recent years, research on exosomes and their content has been intensive, which has
revealed their important role in cell‑to‑cell communication, and has implicated exosomal …

Placental extracellular vesicles in maternal-fetal communication during pregnancy

C Martin, M Bergamelli, CE Malnou… - Biochemical Society …, 2022 - portlandpress.com
For several years, a growing number of studies have highlighted the pivotal role of placental
extracellular vesicles (EVs) throughout pregnancy. These membrane nanovesicles …

Extracellular vesicles in gestational diabetes mellitus: A scoping review

T Bathla, A Abolbaghaei, AB Reyes… - … and Vascular Disease …, 2022 - journals.sagepub.com
Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy
worldwide. Despite extensive study, the molecular mechanisms leading to GDM and …

Proteomics studies in gestational diabetes mellitus: a systematic review and meta-analysis

N Sriboonvorakul, J Hu, D Boriboonhirunsarn… - Journal of Clinical …, 2022 - mdpi.com
Gestational Diabetes Mellitus (GDM) is the most common metabolic complication during
pregnancy and is associated with serious maternal and fetal complications such as pre …

Comparison of plasma exosome proteomes between obese and non-obese patients with type 2 diabetes mellitus

Y Wang, Y Wu, S Yang, Y Chen - Diabetes, Metabolic Syndrome …, 2023 - Taylor & Francis
Purpose Obesity is considered a promoter of type 2 diabetes mellitus (T2DM). However, the
underlying mechanism remains unclear. This study aimed to identify plasma exosome …

Recent progress in mass spectrometry-based urinary proteomics

N Joshi, K Garapati, V Ghose, RK Kandasamy… - Clinical Proteomics, 2024 - Springer
Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

A critical review of proteomic studies in gestational diabetes mellitus

T Zhou, L Huang, M Wang, D Chen… - Journal of Diabetes …, 2020 - Wiley Online Library
Gestational diabetes mellitus is a progressive and complex pregnancy complication, which
threatens both maternal and fetal health. It is urgent to screen for specific biomarkers for …