Formulation optimization and characterization of carvacrol-loaded nanoemulsions: In vitro antibacterial activity/mechanism and safety evaluation

Q Liu, Z Wang, A Mukhamadiev, J Feng, Y Gao… - Industrial Crops and …, 2022 - Elsevier
Practical application of carvacrol in different fields including foods and biopesticides is
limited because of its instability and water insolubility. To overcome these problems …

Development of oral lipid based nano-formulation of dapagliflozin: optimization, in vitro characterization and ex vivo intestinal permeation study

A Zafar - Journal of Oleo Science, 2020 - jstage.jst.go.jp
The oral route is the most prevalent route of drug administration among various routes.
Dapagliflozin is an oral hypoglycemic drug used for lowering the blood glucose level. The …

Hydrochlorothiazide/losartan potassium tablet prepared by direct compression

Q Luo, Q Zhang, P Wang - Pharmaceutics, 2022 - mdpi.com
Hydrochlorothiazide (HCTZ)/losartan potassium (LOS-K) was used as a model drug to
prepare compound tablets through the investigation of the compression and mechanical …

Niclosamide nanoemulsion for colorectal cancer: development, physicochemical characterization, and in vitro anticancer activity

EJ Barbosa, C Fukumori, S de Araújo Sprengel… - Journal of Nanoparticle …, 2024 - Springer
Abstract The BCS class II (Biopharmaceutical Classification System) niclosamide has shown
promising anticancer activity for colorectal cancer. However, its low water solubility …

Hydroxymethylnitrofurazone lymphatic uptake with nanostructured lipid carrier after oral administration in rats

A Souza, CB Scarim, PC Cotrim, FB Junior… - …, 2024 - Taylor & Francis
Background: Leishmaniasis, caused by the protozoan Leishmania sp., infects phagocyte
cells present in lymphatic organs. This study demonstrates the influence of nanostructured …

The Development of Magnolol-Loaded Intravenous Emulsion with Low Hepatotoxic Potential

A Gostyńska, J Czerniel, J Kuźmińska, I Żółnowska… - Pharmaceuticals, 2023 - mdpi.com
Intestinal failure-associated liver disease (IFALD) is a severe liver injury occurring due to
factors related to intestinal failure and parenteral nutrition administration. Different …

An update on lipid-based nanodrug delivery systems for leishmaniasis treatment

VS Mishra, P Tiwari, M Gupta, PK Gupta - Nanomedicine, 2023 - Taylor & Francis
Full article: An Update on Lipid-Based Nanodrug Delivery Systems for Leishmaniasis Treatment
Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …

Development of an HPLC method for identification and quantification of anti-leishmaniasis drug candidate NFOH after oral administration of NLC-NFOH in rats

A de Souza, MKL de Almeida, JA Barbosa… - Chemistry Africa, 2023 - Springer
Hydroxymethylnitrofurazone (NFOH) is a prodrug synthesized from the original nitrofurazone
compound (NF). NFOH has shown activity in vivo against Trypanosoma cruzi and in vitro …

Actinide Decorporation: A Review on Chelation Chemistry and Nanocarriers for Pulmonary Administration

EPC Lai, C Li - Radiation Research, 2022 - meridian.allenpress.com
Chelation is considered the best method for detoxification by promoting excretion of
actinides (Am, Np, Pu, Th, U) from the human body after internal contamination. Chemical …

Quality by design based development of nanostructured lipid carrier: a risk based approach

T Alam - Exploration of Medicine, 2022 - explorationpub.com
The aim of this review is to discuss the development of nanostructured lipid carrier (NLC) by
the application of quality by design (QbD). QbD started with the evolution of the quality …