Volatile general anesthetics continue to be an important part of clinical anesthesia
worldwide. The impact of volatile anesthetics on the immune system has been investigated …

Cancer is a leading cause of morbidity and mortality worldwide and the ratio of incidence is
increasing. Mortality usually results from recurrence or metastases. Surgical removal of the …

Background Animal models and retrospective clinical data suggest that certain anaesthetic
techniques can attenuate immunosuppression and minimize metastasis after cancer …

Purpose Mortality among cancer patients is more commonly due to the effects of metastasis
and recurrence as opposed to the primary tumour. Various perioperative factors have been …

Background Perioperative strategies can significantly influence long-term cancer outcomes.
Dexmedetomidine, an α 2-adrenoceptor agonist, is increasingly used perioperatively for its …

Introduction: Perioperative anesthesia and analgesia exacerbate immunosuppression in
immunocompromised cancer patients. The natural killer (NK) cell is a critical part of anti …

Background In vitro and retrospective clinical studies suggest an association between
anaesthetic technique during primary breast cancer surgery and cancer outcome. Apoptosis …

Surgical removal of the primary tumor in solid cancer is an essential component of the
treatment. However, the perioperative period can paradoxically lead to an increased risk of …

Background: Live animal studies using an inoculation model of breast cancer indicate that
anaesthetic drugs and techniques differentially affect cancer metastasis, inversely related to …

Neuroendocrine differentiation (NED) marks a structural and functional feature of certain
cancers, including prostate cancer (PCa), whereby the malignant tissue contains a …