Vascular smooth muscle cells in intimal hyperplasia, an update

S Déglise, C Bechelli, F Allagnat - Frontiers in physiology, 2023 - frontiersin.org
Arterial occlusive disease is the leading cause of death in Western countries. Core
contemporary therapies for this disease include angioplasties, stents, endarterectomies and …

[HTML][HTML] Targeting smooth muscle cell phenotypic switching in vascular disease

R Chakraborty, P Chatterjee, JM Dave, AC Ostriker… - JVS-vascular …, 2021 - Elsevier
Objective The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …

Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

SR Mehta, S Yusuf, RJG Peters, ME Bertrand… - The Lancet, 2001 - thelancet.com
Background Despite the use of aspirin, there is still a risk of ischaemic events after
percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to …

Optical projection tomography as a tool for 3D microscopy and gene expression studies

J Sharpe, U Ahlgren, P Perry, B Hill, A Ross… - Science, 2002 - science.org
Current techniques for three-dimensional (3D) optical microscopy (deconvolution, confocal
microscopy, and optical coherence tomography) generate 3D data by “optically sectioning” …

Guidelines for percutaneous coronary interventions: the Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology

S Silber, P Albertsson, FF Avilés… - European heart …, 2005 - academic.oup.com
In patients with stable CAD, PCI can be considered a valuable initial mode of
revascularization in all patients with objective large ischaemia in the presence of almost …

Role of Prostacyclin in the Cardiovascular Response to Thromboxane A2

Y Cheng, SC Austin, B Rocca, BH Koller, TM Coffman… - Science, 2002 - science.org
Thromboxane (Tx) A2 is a vasoconstrictor and platelet agonist. Aspirin affords
cardioprotection through inhibition of TxA2 formation by platelet cyclooxygenase (COX-1) …

Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases

TE Van Dyke, CN Serhan - Journal of dental research, 2003 - journals.sagepub.com
The periodontal diseases are infectious diseases caused by predominantly Gram-negative
bacteria. However, as our understanding of the pathogenesis of the periodontal diseases …

Clinical aspects of platelet inhibitors and thrombus formation

TA Meadows, DL Bhatt - Circulation research, 2007 - Am Heart Assoc
The platelet, once thought to be solely involved in clot formation, is now known to be a key
mediator in various others processes such as inflammation, thrombosis, and atherosclerosis …

Macrophage differentiation to foam cells

P Shashkin, B Dragulev, K Ley - Current pharmaceutical design, 2005 - ingentaconnect.com
Foam cell formation from macrophages with subsequent fatty streak formation plays a key
role in early atherogenesis. Foam cell formation is thought to be induced by Low Density …

Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial

MG Bousser, P Amarenco, A Chamorro, M Fisher… - The Lancet, 2011 - thelancet.com
Background Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high
risk of recurrent stroke or other cardiovascular events. We compared the selective …