Antigen presentation in cancer—mechanisms and clinical implications for immunotherapy
Over the past decade, the emergence of effective immunotherapies has revolutionized the
clinical management of many types of cancers. However, long-term durable tumour control …
clinical management of many types of cancers. However, long-term durable tumour control …
Mining the immunopeptidome for antigenic peptides in cancer
RA León-Letelier, H Katayama, S Hanash - Cancers, 2022 - mdpi.com
Simple Summary The immunopeptidome of cancer cells is a treasure trove of neoantigens
bound to MHC molecules, thus a great source for mining immunopeptides for …
bound to MHC molecules, thus a great source for mining immunopeptides for …
Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning
JB Nilsson, S Kaabinejadian, H Yari, MGD Kester… - Science …, 2023 - science.org
Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II
molecules is crucial for rational development of immunotherapies and vaccines targeting …
molecules is crucial for rational development of immunotherapies and vaccines targeting …
The necessary role of an efficient tumor immunotherapy by MHC II expression on amateur APCs
J Zhong, X Lin, H Hu - Malignancy Spectrum, 2024 - Wiley Online Library
Antigen presentation, as the initial step in inducing the activation of T lymphocytes, plays a
crucial role in antitumor response. Studies concentrating on major histocompatibility …
crucial role in antitumor response. Studies concentrating on major histocompatibility …
[PDF][PDF] Mining the Immunopeptidome for Antigenic Peptides in Cancer.
RA León-Letelier, H Katayama, S Hanash - Cancers, 2022 - pdfs.semanticscholar.org
Although harnessing the immune system for cancer therapy has shown success, response
to immunotherapy has been limited. The immunopeptidome of cancer cells presents an …
to immunotherapy has been limited. The immunopeptidome of cancer cells presents an …