Active matter, which ranges from molecular motors to groups of animals, exists at different
length scales and timescales, and various computational models have been proposed to …

Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

The molecular requirements and morphology of migrating cells can vary depending on
matrix geometry; therefore, predicting the optimal migration strategy or the effect of …

Motile eukaryotic cells polarize in response to external signals. Numerous mechanisms
have been suggested to account for this symmetry breaking and for the ensuing robust …

Despite their overwhelming complexity, living cells display a high degree of internal
mechanical and functional organization which can largely be attributed to the intracellular …

Polarization, a primary step in the response of an individual eukaryotic cell to a spatial
stimulus, has attracted numerous theoretical treatments complementing experimental …

Chemotaxis in eukaryotic cells involves the coordination of several related but separable
processes: motility, polarization, and gradient sensing. Mathematical models that have been …

Motile cells—fan-like keratocytes, hand-shaped nerve growth cones, polygonal fibroblasts,
to name but a few—come in different shapes and sizes. We discuss the origins of this …

A migrating cell is a molecular machine made of tens of thousands of short-lived and
interacting parts. Understanding migration means understanding the self-organization of …