The role of neutrophil extracellular traps in cancer progression, metastasis and therapy

Y Chen, H Hu, S Tan, Q Dong, X Fan, Y Wang… - … Hematology & Oncology, 2022 - Springer
Neutrophil extracellular traps (NETs) released by activated neutrophils typically consist of
DNA-histone complexes and granule proteins. NETs were originally identified as a host …

Regulation of neutrophil extracellular traps in cancer

J Xia, Z Zhang, Y Huang, Y Wang… - International Journal of …, 2024 - Wiley Online Library
Neutrophil extracellular trap (NET) is one of the defense functions of neutrophils, which has
a rapid ability to kill infections and is also crucial in a variety of immune‐associated diseases …

[HTML][HTML] Mechanisms of neutrophil extracellular trap in chronic inflammation of endothelium in atherosclerosis

X Yang, Y Ma, X Chen, J Zhu, W Xue, K Ning - Life Sciences, 2023 - Elsevier
Cardiovascular diseases are a primary cause of morbidity and mortality around the world. In
addition, atherosclerosis (AS)-caused cardiovascular disease is the primary cause of death …

Immune checkpoint inhibitors, small-molecule immunotherapies and the emerging role of neutrophil extracellular traps in therapeutic strategies for head and neck …

CH O'Meara, Z Jafri, LM Khachigian - International Journal of Molecular …, 2023 - mdpi.com
Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancer
types, including head and neck cancers (HNC). When checkpoint and partner proteins bind …

Neutrophil extracellular traps in tumor progression and immunotherapy

M Yan, Y Gu, H Sun, Q Ge - Frontiers in Immunology, 2023 - frontiersin.org
Tumor immunity is a growing field of research that involves immune cells within the tumor
microenvironment. Neutrophil extracellular traps (NETs) are neutrophil-derived extracellular …

A neutrophil extracellular traps signature predicts the clinical outcomes and immunotherapy response in head and neck squamous cell carcinoma

N Chen, D He, J Cui - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Background: Neutrophil extracellular traps (NETs) play an important role in the occurrence,
metastasis and immune escape of cancers. This study aimed to investigate NET-related …

Intratumoral neutrophil extracellular traps are associated with unfavorable clinical outcomes and immunogenic context in pancreatic ductal adenocarcinoma

X Chen, H Ma, S Mo, S Yu, Z Lu, J Chen - Frontiers in Immunology, 2022 - frontiersin.org
Extracellular traps (ETs) and tumor-infiltrating immune cells play crucial roles in tumor
progression. However, little is known about the clinical significance of tumor-infiltrating …

Neutrophil extracellular trap-associated risk index for predicting outcomes and response to Wnt signaling inhibitors in triple-negative breast cancer

Z Huang, J Wang, B Sun, M Qi, S Gao, H Liu - Scientific Reports, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a type of breast cancer with poor prognosis, which
is prone to distant metastasis and therapy resistance. The presence of neutrophil …

Роль нетоза в патогенезе иммуновоспалительных ревматических заболеваний

ЕЛ Насонов, АС Авдеева… - Научно …, 2023 - rsp.mediar-press.net
Аннотация Неконтролируемая активация нейтрофилов рассматривается как важный
механизм тромбовоспаления и фиброза при иммуновоспалительных ревматических …

[HTML][HTML] Tbp and Hprt1 Are Appropriate Reference Genes for Splenic Neutrophils Isolated from Healthy or Tumor-Bearing Mice

K Sounbuli, LA Alekseeva, AV Sen'kova, IA Savin… - Biomedicines, 2024 - mdpi.com
Background/Objectives: Neutrophils have recently gained significant attention due to their
heterogeneity in tumor settings. The gene expression profiles of neutrophils from different …