Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer …

CJ Tsai, JT Yang, N Shaverdian, J Patel, AF Shepherd… - The Lancet, 2024 - thelancet.com
Background Most patients with metastatic cancer eventually develop resistance to systemic
therapy, with some having limited disease progression (ie, oligoprogression). We aimed to …

[HTML][HTML] Oligoprogression in non-small cell lung cancer

D Harada, N Takigawa - Cancers, 2021 - mdpi.com
Simple Summary Several retrospective studies present evidence of oligoprogressive
disease (OPD) in patients with non-small cell lung cancer (NSCLC) with driver mutations …

Stereotactic radiotherapy for oligoprogression in metastatic renal cell cancer patients receiving tyrosine kinase inhibitor therapy: a phase 2 prospective multicenter …

P Cheung, S Patel, SA North, A Sahgal, W Chu… - European Urology, 2021 - Elsevier
Background Despite the paucity of prospective evidence, stereotactic radiotherapy (SRT) is
increasingly being considered in the setting of oligoprogression to delay the need to change …

Patterns of failure, low-volume relapse, and subsequent ablative management in locally advanced non-small cell lung cancer treated with definitive chemoradiation …

C Friedes, M Iocolano, SH Lee, B Li, L Duan… - International Journal of …, 2024 - Elsevier
Purpose The objective of this study was to describe the patterns of failure, frequency of low-
volume relapse (LVR), and candidacy for ablative therapy at time of disease progression …

Patterns of Failure in Metastatic NSCLC Treated With First Line Pembrolizumab and Use of Local Therapy in Patients With Oligoprogression

C Friedes, N Yegya-Raman, S Zhang, M Iocolano… - Clinical Lung Cancer, 2024 - Elsevier
Introduction The patterns of failure (POF) for metastatic non–small-cell lung cancer
(mNSCLC) treated with immunotherapy are not well established. Methods We conducted a …

[HTML][HTML] Oligo-residual disease in PD-1/PD-L1 inhibitor-treated metastatic non-small cell lung cancer: incidence, pattern of failure, and clinical value of local …

J Zhang, J Gao, S Jiang, J Mao, L Chu, X Chu… - Cancer Immunology …, 2024 - Springer
Objectives To investigate the feasibility and potential clinical value of local consolidative
therapy (LCT) in PD-1/PD-L1 inhibitor-treated metastatic non-small cell lung cancer …

The Emerging Role of Radiotherapy in Oligoprogressive Non-Small Cell Lung Cancer

A Tam, N Eustace, A Kassardjian… - Surgical Oncology …, 2023 - surgonc.theclinics.com
Recent advances in targeted therapies have made significant progress in improving survival
outcomes in patients with many types of cancer. In non-small cell lung cancer (NSCLC) …

Late metastatic presentation is associated with improved survival and delayed wide‐spread progression after ablative stereotactic body radiotherapy for …

X Chen, H Chen, I Poon, D Erler, S Badellino… - Cancer …, 2021 - Wiley Online Library
Background Stereotactic body radiotherapy (SBRT) is increasingly used to treat
oligometastatic disease (OMD), but the effect of metastasis timing on patient outcomes …

[HTML][HTML] Estimating survival and clinical outcome in advanced non-small cell lung cancer with bone-only metastasis using molecular markers

C Meng, J Wei, J Tian, J Ma, N Liu, Z Yuan… - Journal of Bone …, 2021 - Elsevier
Objectives This retrospective study investigated prognostic factors in advanced non-small
cell lung cancer (NSCLC) with bone-only metastasis, and developed a graded prognostic …

Is stereotactic body radiotherapy an effective treatment in metastatic lung cancer with oligoprogressive disease?

M Aquilano, M Loi, L Visani, L Livi, JJ Nuyttens - Acta Oncologica, 2023 - Taylor & Francis
Background Oligoprogression (OPD) is defined as a condition where limited progression (1–
3 metastases) is observed in patients undergoing systemic cancer treatment. In this study we …