[HTML][HTML] The synaptic hypothesis of schizophrenia version III: a master mechanism
OD Howes, EC Onwordi - Molecular Psychiatry, 2023 - nature.com
The synaptic hypothesis of schizophrenia has been highly influential. However, new
approaches mean there has been a step-change in the evidence available, and some tenets …
approaches mean there has been a step-change in the evidence available, and some tenets …
An overview of animal models related to schizophrenia
Schizophrenia is a heterogeneous psychiatric disorder that is poorly treated with current
therapies. In this brief review, we provide an update regarding the use of animal models to …
therapies. In this brief review, we provide an update regarding the use of animal models to …
Animal models of schizophrenia
CA Jones, DJG Watson… - British journal of …, 2011 - Wiley Online Library
Developing reliable, predictive animal models for complex psychiatric disorders, such as
schizophrenia, is essential to increase our understanding of the neurobiological basis of the …
schizophrenia, is essential to increase our understanding of the neurobiological basis of the …
Neurobiological bases of autism–epilepsy comorbidity: a focus on excitation/inhibition imbalance
Y Bozzi, G Provenzano… - European Journal of …, 2018 - Wiley Online Library
Autism spectrum disorders (ASD) and epilepsy are common neurological diseases of
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …
Cortical inhibitory neurons and schizophrenia
DA Lewis, T Hashimoto, DW Volk - Nature Reviews Neuroscience, 2005 - nature.com
Impairments in certain cognitive functions, such as working memory, are core features of
schizophrenia. Convergent findings indicate that a deficiency in signalling through the TrkB …
schizophrenia. Convergent findings indicate that a deficiency in signalling through the TrkB …
[HTML][HTML] Reelin functions, mechanisms of action and signaling pathways during brain development and maturation
Y Jossin - Biomolecules, 2020 - mdpi.com
During embryonic development and adulthood, Reelin exerts several important functions in
the brain including the regulation of neuronal migration, dendritic growth and branching …
the brain including the regulation of neuronal migration, dendritic growth and branching …
Extracellular matrix: functions in the nervous system
CS Barros, SJ Franco, U Müller - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
An astonishing number of extracellular matrix glycoproteins are expressed in dynamic
patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia …
patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia …
[HTML][HTML] Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning
EJ Weeber, U Beffert, C Jones, JM Christian… - Journal of Biological …, 2002 - ASBMB
Two apolipoprotein E (apoE) receptors, the very low density lipoprotein (VLDL) receptor and
apoE receptor 2 (apoER2), are also receptors for Reelin, a signaling protein that regulates …
apoE receptor 2 (apoER2), are also receptors for Reelin, a signaling protein that regulates …
Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices
BACKGROUND: A limited number of reports have demonstrated abnormalities involving the
glutamate and gamma amino butyric acid systems in blood and platelets of subjects with …
glutamate and gamma amino butyric acid systems in blood and platelets of subjects with …
Sex differences in oxytocin and vasopressin: implications for autism spectrum disorders?
CS Carter - Behavioural brain research, 2007 - Elsevier
Autism spectrum disorders (ASD) are male-biased and characterized by deficits in social
behavior and social communication, excessive anxiety or hyperreactivity to stressful …
behavior and social communication, excessive anxiety or hyperreactivity to stressful …