Virtual clinical trials in medical imaging: a review

E Abadi, WP Segars, BMW Tsui… - Journal of Medical …, 2020 - spiedigitallibrary.org
The accelerating complexity and variety of medical imaging devices and methods have
outpaced the ability to evaluate and optimize their design and clinical use. This is a …

Approximating the ideal observer and hotelling observer for binary signal detection tasks by use of supervised learning methods

W Zhou, H Li, MA Anastasio - IEEE transactions on medical …, 2019 - ieeexplore.ieee.org
It is widely accepted that the optimization of medical imaging system performance should be
guided by task-based measures of image quality (IQ). Task-based measures of IQ quantify …

A deep learning‐and partial least square regression‐based model observer for a low‐contrast lesion detection task in CT

H Gong, L Yu, S Leng, SK Dilger, L Ren… - Medical …, 2019 - Wiley Online Library
Purpose This work aims to develop a new framework of image quality assessment using
deep learning‐based model observer (DL‐MO) and to validate it in a low‐contrast lesion …

Learning stochastic object models from medical imaging measurements by use of advanced ambient generative adversarial networks

W Zhou, S Bhadra, FJ Brooks, H Li… - Journal of Medical …, 2022 - spiedigitallibrary.org
Purpose: To objectively assess new medical imaging technologies via computer-
simulations, it is important to account for the variability in the ensemble of objects to be …

Approximating the ideal observer for joint signal detection and localization tasks by use of supervised learning methods

W Zhou, H Li, MA Anastasio - IEEE transactions on medical …, 2020 - ieeexplore.ieee.org
Medical imaging systems are commonly assessed and optimized by use of objective
measures of image quality (IQ). The Ideal Observer (IO) performance has been advocated to …

Ideal observer computation by use of Markov-chain Monte Carlo with generative adversarial networks

W Zhou, U Villa, MA Anastasio - IEEE transactions on medical …, 2023 - ieeexplore.ieee.org
Medical imaging systems are often evaluated and optimized via objective, or task-specific,
measures of image quality (IQ) that quantify the performance of an observer on a specific …

Markov-chain monte carlo approximation of the ideal observer using generative adversarial networks

W Zhou, MA Anastasio - Medical Imaging 2020: Image …, 2020 - spiedigitallibrary.org
The Ideal Observer (IO) performance has been advocated when optimizing medical imaging
systems for signal detection tasks. However, analytical computation of the IO test statistic is …

Task-based performance evaluation of deep neural network-based image denoising

K Li, W Zhou, H Li… - Medical Imaging 2021 …, 2021 - spiedigitallibrary.org
Deep neural network (DNN)-based image denoising methods have been proposed for use
with medical images. These methods are commonly optimized and evaluated by use of …

Supervised learning-based ideal observer approximation for joint detection and estimation tasks

K Li, W Zhou, H Li… - Medical Imaging 2021 …, 2021 - spiedigitallibrary.org
The ideal observer (IO) sets an upper performance limit among all observers and has been
advocated for use in assessing and optimizing imaging systems. For joint detection …

Learning the Hotelling observer for SKE detection tasks by use of supervised learning methods

W Zhou, H Li, MA Anastasio - Medical Imaging 2019: Image …, 2019 - spiedigitallibrary.org
Task-based measures of image quality (IQ) quantify the ability of an observer to perform a
specific task. Such measures are commonly employed for assessing and optimizing medical …