Bile acids as modulators of gut microbiota composition and function

AB Larabi, HLP Masson, AJ Bäumler - Gut Microbes, 2023 - Taylor & Francis
Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

A Lavelle, H Sokol - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

[HTML][HTML] The interplay between the gut microbiome and the immune system in the context of infectious diseases throughout life and the role of nutrition in optimizing …

SP Wiertsema, J van Bergenhenegouwen, J Garssen… - Nutrients, 2021 - mdpi.com
Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

W Jia, G Xie, W Jia - Nature reviews Gastroenterology & hepatology, 2018 - nature.com
Emerging evidence points to a strong association between the gut microbiota and the risk,
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …

[HTML][HTML] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

J Chen, N Chia, KR Kalari, JZ Yao, M Novotna… - Scientific reports, 2016 - nature.com
Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both
genetic and environmental factors. The exact nature of the environmental factors …

Precision nutrition and the microbiome, part I: current state of the science

S Mills, C Stanton, JA Lane, GJ Smith, RP Ross - Nutrients, 2019 - mdpi.com
The gut microbiota is a highly complex community which evolves and adapts to its host over
a lifetime. It has been described as a virtual organ owing to the myriad of functions it …

Insights into the Role of Erysipelotrichaceae in the Human Host

NO Kaakoush - Frontiers in cellular and infection microbiology, 2015 - frontiersin.org
Understanding the human gut microbiota has garnered interest from researchers and
clinicians to pharmaceutical companies looking at novel mechanisms to manipulate the …

Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy

JYL Chiang, JM Ferrell - American Journal of Physiology …, 2020 - journals.physiology.org
Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for
maintenance of whole body cholesterol homeostasis. Bile acids are physiological …

Taxonomic profiling and populational patterns of bacterial bile salt hydrolase (BSH) genes based on worldwide human gut microbiome

Z Song, Y Cai, X Lao, X Wang, X Lin, Y Cui… - Microbiome, 2019 - Springer
Background Bile salt hydrolase plays an important role in bile acid-mediated signaling
pathways, which regulate lipid absorption, glucose metabolism, and energy homeostasis …

Functional redundancy-induced stability of gut microbiota subjected to disturbance

A Moya, M Ferrer - Trends in microbiology, 2016 - cell.com
The microbiota should be considered as just another component of the human epigenetic
landscape. Thus, health is also a reflection of the diversity and composition of gut microbiota …