[HTML][HTML] The human transcription factors

SA Lambert, A Jolma, LF Campitelli, PK Das, Y Yin… - Cell, 2018 - cell.com
Transcription factors (TFs) recognize specific DNA sequences to control chromatin and
transcription, forming a complex system that guides expression of the genome. Despite keen …

Transcriptional control of chondrocyte specification and differentiation

CF Liu, WE Samsa, G Zhou, V Lefebvre - Seminars in cell & developmental …, 2017 - Elsevier
A milestone in the evolutionary emergence of vertebrates was the invention of cartilage, a
tissue that has key roles in modeling, protecting and complementing the bony skeleton …

JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles

I Rauluseviciute, R Riudavets-Puig… - Nucleic Acids …, 2024 - academic.oup.com
Abstract JASPAR (https://jaspar. elixir. no/) is a widely-used open-access database
presenting manually curated high-quality and non-redundant DNA-binding profiles for …

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

J Chiou, RJ Geusz, ML Okino, JY Han, M Miller… - Nature, 2021 - nature.com
Genetic risk variants that have been identified in genome-wide association studies of
complex diseases are primarily non-coding. Translating these risk variants into mechanistic …

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

A Khan, O Fornes, A Stigliani, M Gheorghe… - Nucleic acids …, 2018 - academic.oup.com
Abstract JASPAR (http://jaspar. genereg. net) is an open-access database of curated, non-
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …

HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis

IV Kulakovskiy, IE Vorontsov, IS Yevshin… - Nucleic acids …, 2018 - academic.oup.com
We present a major update of the HOCOMOCO collection that consists of patterns
describing DNA binding specificities for human and mouse transcription factors. In this …

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

A Mathelier, O Fornes, DJ Arenillas, C Chen… - Nucleic acids …, 2016 - academic.oup.com
Abstract JASPAR (http://jaspar. genereg. net) is an open-access database storing curated,
non-redundant transcription factor (TF) binding profiles representing transcription factor …

AP-1 transcription factors and the BAF complex mediate signal-dependent enhancer selection

T Vierbuchen, E Ling, CJ Cowley, CH Couch, X Wang… - Molecular cell, 2017 - cell.com
Enhancer elements are genomic regulatory sequences that direct the selective expression
of genes so that genetically identical cells can differentiate and acquire the highly …

HOCOMOCO in 2024: a rebuild of the curated collection of binding models for human and mouse transcription factors

IE Vorontsov, IA Eliseeva, A Zinkevich… - Nucleic Acids …, 2024 - academic.oup.com
We present a major update of the HOCOMOCO collection that provides DNA binding
specificity patterns of 949 human transcription factors and 720 mouse orthologs. To make …

Structural features of transcription factors associating with nucleosome binding

MF Garcia, CD Moore, KN Schulz, O Alberto… - Molecular cell, 2019 - cell.com
Fate-changing transcription factors (TFs) scan chromatin to initiate new genetic programs
during cell differentiation and reprogramming. Yet the protein structure domains that allow …