Adverse childhood experiences (ACEs) are associated with poor future mental and physical
health. Altered biological reactivity to mental stress may be a possible mechanism linking …

Severe stress is among the most robust risk factors for the development of psychiatric
disorders. Imaging studies indicate that life stress is integral to shaping the human brain …

Background The impact of coronavirus disease (COVID-19) on public mental health in 2019
is verified, but the role of only-child status in the mental health of adolescents confined at …

Adolescence is a critical period of heightened stress sensitivity and elevated vulnerability for
developing mental illness, suggesting a possible association between stress exposure and …

Background Childhood maltreatment is significantly associated with greater occurrence of
mental disorders in adulthood such as depression and anxiety. As a key node of the limbic …

The importance of amygdala, hippocampus, and medial prefrontal cortex (mPFC) for the
integration of neural, endocrine, and affective stress processing was shown in healthy …

Objective To determine whether childhood maltreatment is associated with immune-
mediated inflammatory disorders (IMIDs; multiple sclerosis [MS], inflammatory bowel …

Trauma can shape the way an individual experiences the world and interacts with other
people. Touch is a key component of social interactions, but surprisingly little is known how …

Background: Childhood maltreatment (CM) is a common psychological stressor associated
with multiple mental disorders. While CM is associated with vulnerability to depression and …

Chronic pain is among the most common reasons adults in the US seek medical care.
Despite chronic pain's substantial impact on individuals' physical, emotional, and financial …