Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is
accumulating evidence to suggest that OA is an inflammatory disease of the entire synovial …

Since publication of the European League Against Rheumatism (EULAR) recommendations
for management of hand osteoarthritis (OA) in 2007 new evidence has emerged. The aim …

Osteoarthritis (OA) most commonly affects knee joints, and the next most commonly affected
sites are the hands and hips. Three distinct hand OA phenotypes have been described …

Role of low-grade inflammation in osteoarthritis : Current Opinion in Rheumatology Role of
low-grade inflammation in osteoarthritis : Current Opinion in Rheumatology Log in or Register …

Osteoarthritis (OA) is a highly prevalent condition, and the hand is the most commonly
affected site. Patients with hand OA frequently report symptoms of pain, functional limitations …

Joint inflammation is present in the majority of OA patients and pro-inflammatory mediators,
such as IL-6, are actively involved in disease progression. Increased levels of IL-6 in serum …

Objective To assess the efficacy, safety, pharmacokinetics and pharmacodynamics of the
anti-interleukin (IL)-1α/β dual variable domain immunoglobulin lutikizumab (ABT-981) in …

Objective To assess the efficacy of adalimumab in patients with erosive hand osteoarthritis
(OA). Method Patients> 50 years old, meeting the American College of Rheumatology (ACR) …

Objective To examine the effect of methotrexate (MTX) on pain and structural progression in
symptomatic erosive hand osteoarthritis (HOA). Methods This 1-year prospective, single …