Characterization of drugs as antioxidant prophylactics
OI Aruoma - Free Radical Biology and Medicine, 1996 - Elsevier
There is growing interest in the evaluation of drugs (prescription only medicines and over-
the-counter medicines) as antioxidant prophylactics. Although free radical mechanism in …
the-counter medicines) as antioxidant prophylactics. Although free radical mechanism in …
1, 4‐Dihydropyridine Derivatives: Dihydronicotinamide Analogues—Model Compounds Targeting Oxidative Stress
A Velena, N Zarkovic, K Gall Troselj… - Oxidative medicine …, 2016 - Wiley Online Library
Many 1, 4‐dihydropyridines (DHPs) possess redox properties. In this review DHPs are
surveyed as protectors against oxidative stress (OS) and related disorders, considering the …
surveyed as protectors against oxidative stress (OS) and related disorders, considering the …
Mechanisms of hydrogen peroxide-induced contraction of rat aorta
Z Yang, T Zheng, A Zhang, BT Altura… - European journal of …, 1998 - Elsevier
It has been suggested that reactive oxygen species may be involved in the regulation of
vascular tone. However, the underlying mechanisms remain to be elucidated. The present …
vascular tone. However, the underlying mechanisms remain to be elucidated. The present …
Biological fate and effects of propranolol in an experimental aquatic food chain
J Ding, G Lu, S Li, Y Nie, J Liu - Science of the Total Environment, 2015 - Elsevier
The aim of this study was to evaluate the trophic transfer of the β-blocker propranolol (PRP)
in an experimental aquatic food chain involving the green algae Scenedesmus obliquus, the …
in an experimental aquatic food chain involving the green algae Scenedesmus obliquus, the …
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation
H Sugawara, K Tobise, K Kikuchi - Hypertension Research, 1996 - jstage.jst.go.jp
We studied the antioxidant effects of nine calcium antagonists (nisoldipine, benidipine,
nilvadipine, felodipine, nicardipine; nitrendipine, nifedipine, verapamil, and diltiazem) by …
nilvadipine, felodipine, nicardipine; nitrendipine, nifedipine, verapamil, and diltiazem) by …
Cardioprotective Effect of Propranolol From Alcohol‐Induced Heart Muscle Damage as Assessed by Plasma Cardiac Troponin‐T
VB Patel, R Ajmal, RA Sherwood… - Alcoholism: Clinical …, 2001 - Wiley Online Library
Background: Heavy alcohol consumption from either long‐term misuse or binge drinking is
associated with poor cardiac contractility, mitochondrial dysfunction, and ventricular …
associated with poor cardiac contractility, mitochondrial dysfunction, and ventricular …
Antioxidant effects of photodegradation product of nifedipine
Y Horinouchi, K Tsuchiya, C Taoka… - Chemical and …, 2011 - jstage.jst.go.jp
Recently, increasing evidence suggests that the antihypertensive drug nifedipine acts as a
protective agent for endothelial cells, and that the activity is unrelated to its calcium channel …
protective agent for endothelial cells, and that the activity is unrelated to its calcium channel …
Structural effects on the reactivity 1, 4-dihydropyridines with alkylperoxyl radicals and ABTS radical cation
C Yanez, C Lopez-Alarcon, C Camargo… - Bioorganic & medicinal …, 2004 - Elsevier
A series of eight commercial C-4 substituted 1, 4-dihydropyridines and other synthesized
related compounds were tested for direct potential scavenger effect towards alkylperoxyl …
related compounds were tested for direct potential scavenger effect towards alkylperoxyl …
Modulation by dihydropyridine‐type calcium channel antagonists of cytokine‐inducible gene expression in vascular smooth muscle cells
The 1, 4‐dihydropyridine nifedipine is frequently used in the therapy of hypertension and
heart failure. In addition, nifedipine has been shown to exert distinct anti‐arteriosclerotic …
heart failure. In addition, nifedipine has been shown to exert distinct anti‐arteriosclerotic …
Reactivity of 1, 4-dihydropyridines toward alkyl, alkylperoxyl radicals, and ABTS radical cation
C López-Alarcón, P Navarrete… - Chemical research in …, 2003 - ACS Publications
A series of C4-substituted 1, 4-dihydropyridines (DHP) with either secondary or tertiary
nitrogen in the dihydropyridine ring were synthesized. All of these compounds together with …
nitrogen in the dihydropyridine ring were synthesized. All of these compounds together with …