Maximizing cellular adaptation to endurance exercise in skeletal muscle
The application of molecular techniques to exercise biology has provided novel insight into
the complexity and breadth of intracellular signaling networks involved in response to …
the complexity and breadth of intracellular signaling networks involved in response to …
Hypoxia-inducible factor as an angiogenic master switch
T Hashimoto, F Shibasaki - Frontiers in pediatrics, 2015 - frontiersin.org
Hypoxia-inducible factors (HIFs) regulate the transcription of genes that mediate the
response to hypoxia. HIFs are constantly expressed and degraded under normoxia, but …
response to hypoxia. HIFs are constantly expressed and degraded under normoxia, but …
Differences in susceptibility to heat stress along the chicken intestine and the protective effects of galacto-oligosaccharides
High ambient temperatures negatively affect the human well-being as well as animal welfare
and production. The gastrointestinal tract is predominantly responsive to heat stress. The …
and production. The gastrointestinal tract is predominantly responsive to heat stress. The …
Thermal biology of domestic animals
RJ Collier, KG Gebremedhin - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
The thermal environment is the most important ecological factor determining the growth,
development, and productivity of domestic animals. Routes of energy exchange (sensible …
development, and productivity of domestic animals. Routes of energy exchange (sensible …
[HTML][HTML] Heat therapy: mechanistic underpinnings and applications to cardiovascular health
Cardiovascular diseases (CVD) are the leading cause of death worldwide, and novel
therapies are drastically needed to prevent or delay the onset of CVD to reduce the societal …
therapies are drastically needed to prevent or delay the onset of CVD to reduce the societal …
Hypoxia and fetal heart development
AJ Patterson, L Zhang - Current molecular medicine, 2010 - ingentaconnect.com
Fetal hearts show a remarkable ability to develop under hypoxic conditions. The metabolic
flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact …
flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact …
Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture
Hypoxia and hyperthermia, which can be induced by high environmental temperature or
strenuous exercise, are two common stressors that affect intestinal epithelial integrity and …
strenuous exercise, are two common stressors that affect intestinal epithelial integrity and …
Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress
The heat shock response (HSR) is a conserved cellular defensive response against stresses
such as temperature, oxidative stress and heavy metals. A significant group of players in the …
such as temperature, oxidative stress and heavy metals. A significant group of players in the …
An overview of protective strategies against ischemia/reperfusion injury: The role of hyperbaric oxygen preconditioning
C Hentia, A Rizzato, E Camporesi, Z Yang… - Brain and …, 2018 - Wiley Online Library
Abstract Introduction Ischemia/reperfusion (I/R) injury, such as myocardial infarction, stroke,
and peripheral vascular disease, has been recognized as the most frequent causes of …
and peripheral vascular disease, has been recognized as the most frequent causes of …
Induction of the heat shock pathway during hypoxia requires regulation of heat shock factor by hypoxia-inducible factor-1
NA Baird, DW Turnbull, EA Johnson - Journal of Biological Chemistry, 2006 - ASBMB
Activation of heat shock proteins (Hsps) is critical to adaptation to low oxygen levels
(hypoxia) and for enduring the oxidative stress of reoxygenation. Hsps are known to be …
(hypoxia) and for enduring the oxidative stress of reoxygenation. Hsps are known to be …