Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but
also by visual, olfactory, and imaginary stimuli. The reflex involves both autonomic and …

The eighth edition of Goldfrank's Toxicologic Emergencies is the quadrennial update of the
standard for medical toxicology text books. Several new medical toxicology textbooks have …

Since introduction of the PDE-5 inhibitor sildenafil 4 years ago, there has been a
fundamental change in the treatment of erectile dysfunction (ED). Intracavernosal or …

Erectile dysfunction (ED) is defined as the consistent inability to obtain or maintain an
erection for satisfactory sexual intercourse. Basic science research on erectile physiology …

By using a combination of genetic, pharmacological, and anatomical approaches, we show
that the melanocortin 4 receptor (MC4R), implicated in the control of food intake and energy …

PURPOSE: The importance of signaling pathways in penile smooth muscles involved in
normal erection and erectile dysfunction (ED) is discussed based on a review of the …

The paraventricular nucleus of the hypothalamus is an integration centre between the
central and peripheral autonomic nervous systems. It is involved in numerous functions from …

Since the early 1980s, research on the mechanisms of penile erection has done much to
clarify erectile physiology and pathophysiology. More recent studies have identified the …

Recent experimental evidence suggests that arterial insufficiency precedes the structural
and functional changes in corpora cavernosa (CC) leading to organic erectile dysfunction …