With the aging of global population, the incidence of nonalcoholic fatty liver disease
(NAFLD) has surged in recent decades. NAFLD is a multifactorial disease that follows a …

Liver cancer is the second most frequent cause of cancer-related death globally. The main
histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes …

The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH)
in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated …

Liver cancer is one of the most common cancer types worldwide and the fourth leading
cause of cancer-related death. Liver carcinoma is distinguished by a high heterogeneity in …

Hepatitis virus infection is a leading cause of chronic liver disease, including cirrhosis and
hepatocellular carcinoma (HCC). Although anti-viral therapies against hepatitis B virus …

Systemic chemotherapy using a multitargeted tyrosine kinase inhibitor is an established
treatment for advanced‐stage tumors in various organs. Comprehensive genomic analyses …

Telomerase reverse transcriptase (TERT) mutation is the most frequent genetic alteration in
hepatocellular carcinoma (HCC). Our aims were to investigate whether TERT mutations can …

This study focused on studying the impact of flavonoids isolated from Cleome droserifolia on
HCC cell lines and to further unveil their possible impact on TP53 and its downstream tumor …

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. 1
HCC prevalence and attributable mortality in the United States are increasing rapidly, 2, 3 …

Nonalcoholic fatty liver disease (NAFLD) is the leading contributor to the global burden of
chronic liver diseases. The phenotypic umbrella of NAFLD spans from simple and reversible …