Adenosine and brain function

BB Fredholm, JF Chen, RA Cunha… - Int Rev …, 2005 - books.google.com
A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …

Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs

BB Fredholm, JF Chen, SA Masino… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract Adenosine and its receptors have been the topic of many recent reviews (–).
These reviews provide a good summary of much of the relevant literature—including the …

Caffeine for treatment of Parkinson disease: a randomized controlled trial

RB Postuma, AE Lang, RP Munhoz, K Charland… - Neurology, 2012 - AAN Enterprises
Objective: Epidemiologic studies consistently link caffeine, a nonselective adenosine
antagonist, to lower risk of Parkinson disease (PD). However, the symptomatic effects of …

Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

D Masini, O Kiehn - Nature communications, 2022 - nature.com
The pedunculopontine nucleus (PPN) is a locomotor command area containing
glutamatergic neurons that control locomotor initiation and maintenance. These motor …

Caffeine and the dopaminergic system

O Cauli, M Morelli - Behavioural pharmacology, 2005 - journals.lww.com
Caffeine is the most widely consumed psychostimulant substance, being self-administered
throughout a wide range of conditions and present in numerous dietary products. Due to its …

Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice

PH Botton, MS Costa, AP Ardais, S Mioranzza… - Behavioural brain …, 2010 - Elsevier
Caffeine is a psychostimulant with positive effects on cognition. Recent studies have
suggested the participation of the cholinergic system in the effects of caffeine on …

Haloperidol‐induced catalepsy as an animal model for parkinsonism: A systematic review of experimental studies

I Waku, MS Magalhaes, CO Alves… - European Journal of …, 2021 - Wiley Online Library
Several useful animal models for parkinsonism have been developed so far. Haloperidol‐
induced catalepsy is often used as a rodent model for the study of motor impairments …

[HTML][HTML] The adenosine receptor antagonist, 7-methylxanthine, alters emmetropizing responses in infant macaques

LF Hung, B Arumugam, L Ostrin, N Patel… - … & visual science, 2018 - jov.arvojournals.org
Purpose: Previous studies suggest that the adenosine receptor antagonist, 7-methylxanthine
(7-MX), retards myopia progression. Our aim was to determine whether 7-MX alters the …

Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain

N Shioda, Y Yamamoto, M Watanabe… - Journal of …, 2010 - Soc Neuroscience
Fatty acid binding proteins (FABPs) are essential for energy production and long-chain
polyunsaturated fatty acid-related signaling in the brain and other tissues. Of various FABPs …

Systemic 7-methylxanthine in retarding axial eye growth and myopia progression: a 36-month pilot study

K Trier, S Munk Ribel-Madsen, D Cui… - Journal of ocular biology …, 2008 - Springer
Abstract The adenosine antagonist 7-methylxanthine (7-mx) works against myopia in animal
models. In a clinical trial, 68 myopic children (mean age 11.3 years) received either placebo …