Abstract CD95 (Fas/APO-1) and its ligand, CD95L, have long been viewed as a death
receptor/death ligand system that mediates apoptosis induction to maintain immune …

To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …

Micro (mi) RNAs are small, highly conserved noncoding RNAs that control gene expression
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …

Apoptosis ligand 2 tumor necrosis factor (TNF)-related apoptosis-inducing ligand
(Apo2L/TRAIL) belongs to a small subset of proapoptotic protein ligands in the TNF …

Apoptosis, the cell's intrinsic death program, is a key regulator of tissue homeostasis. An
imbalance between cell death and proliferation may result in tumor formation. Also, killing of …

The early phases of carcinogenesis resemble embryonic development, often involving the
reexpression of embryonic mesenchymal genes. The NCI60 panel of human tumor cell lines …

Micro (mi) RNAs are emerging as important regulators of cellular differentiation, their
importance underscored by the fact that they are often dysregulated during carcinogenesis …

Macroautophagy (generally referred to as autophagy) mediates the bulk degradation of
cytoplasmic contents, including proteins and organelles, in lysosomes. Rapamycin, a …

The CD95 Receptor: Apoptosis Revisited: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research Submit Log …

The apoptosis‐inducing death receptor CD95 (APO‐1/Fas) controls the homeostasis of
many tissues. Despite its apoptotic potential, most human tumors are refractory to the …