Many of the scientific and regulatory challenges that exist in research on the safety, quality
and efficacy of dietary supplements are common to all countries as the marketplace for them …

For three decades, the US Public Health Service has recommended that all persons capable
of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects …

Abstract Background Using the National Birth Defects Prevention Network (NBDPN) annual
data report, US national prevalence estimates for major birth defects are developed based …

The objective of this guideline is to provide recommendations on the consumption of free
sugars to reduce the risk of NCDs in adults and children particularly focusing on the …

Importance Uncertainty remains about the efficacy of folic acid therapy for the primary
prevention of stroke because of limited and inconsistent data. Objective To test the primary …

This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …

In 1992, the US Public Health Service recommended that all women capable of becoming
pregnant consume 400 µg of folic acid daily to prevent neural tube defects (NTDs)(1). NTDs …

Background To examine the prospective association between multivitamin supplementation
during pregnancy and biomarker measures of maternal plasma folate and vitamin B12 …

With 4 mg folic acid daily, it may take 20 weeks to reach red-blood-cell folate levels between
1050 and 1340 nmol/L, optimal for reduction of the neural tube defect risk. Therefore, folic …