In the guinea pig ileum myenteric plexus—longitudinal muscle preparation, dynorphin-(1—
13) and the prototypical κ agonist ethylketocyclazocine had equally poor sensitivity to …

With the exception of the use of adrenocorticotropic hormone (ACTH) as an antipyretic, this
area of thermoregulatory pharmacology is quite recent (Table 1). A compilation (Clark …

1 Nociceptive thresholds to noxious mechanical (paw pressure) and thermal (tail flick)
stimuli were recorded in conscious rats. The effects of three selective κ‐opioid receptor …

The distribution of dynorphin in the central nervous system was investigated in rats
pretreated with relatively high doses (300–400 μg) of colchicine administered …

The immunocytochemical distribution of [Leulenkephalin and an adrenal enkephalin
precursor fragment (BAM-22P) immunoreactivity was investigated in the diencephalon and …

Opioid receptors are differentially coupled to ion channels. Mu-and delta-opioid receptors
are coupled to calcium-and/or voltage-dependent potassium channels and kappa-opioid …

Concentrations of free 3-methoxy-4-hydroxyphenylglycol in the plasma and cerebrospinal
fluid are highly correlated, but concentrations in the cerebrospinal fluid are always higher …

Abstract Dynorphin-(1–17) produces a highly specific increase in food ingestion. Similar
enhancement of food ingestion is found with dynorphin fragments (1–10),(1–11),(1–13) and …

We compared effects on motor function of four peptides belonging to the dynorphin family--
dynorphin-(1-17)(DYN-(1-17], dynorphin-(1-13)(DYN-(1-13], dynorphin-(1-8)(DYN-(1-8] and …

The effects of treatment with the selective kappa-opioid receptor agonist U-69593 upon
cocaine-induced changes in locomotor activity and stereotypy were examined in rats. U …